Evidence map›Paper›PMID 25035773›Full record

ArticleInternational journal of clinical and experimental medicine2014

Tumor suppressor TSLC1 inhibits growth, proliferation, invasiveness and angiogenesis in nude mice xenografted tumor of Eca109 cells.

Qi-Lian Liang, Guo-Qiang Chen, Qiu-Long Liu, Zhou-Yu Li, Xiang-Ning Zhang, Yuan Zhou, Wen-Ting Ou, Bi-Rong Wang, Li-Ren Hu

Abstract read
In one paragraph

Article in International journal of clinical and experimental medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Qi-Lian LiangDepartment of Oncology, Affiliated Hospital of Guangdong Medical College Zhanjiang, 524001, China.
Guo-Qiang ChenDepartment of Oncology, Affiliated Hospital of Guangdong Medical College Zhanjiang, 524001, China.
Qiu-Long LiuDepartment of Oncology, Affiliated Hospital of Guangdong Medical College Zhanjiang, 524001, China.
Zhou-Yu LiDepartment of Radiotherapy, Cancer Center of Guangzhou Medical University Guangzhou, 510095, China.
Xiang-Ning ZhangDepartment of Pathophysiology, School of Basic Medical Science, Guangdong Medical College Dongguan, 523808, China.
Yuan ZhouDepartment of Oncology, Affiliated Hospital of Guangdong Medical College Zhanjiang, 524001, China.
Wen-Ting OuDepartment of Oncology, Affiliated Hospital of Guangdong Medical College Zhanjiang, 524001, China.
Bi-Rong WangDepartment of Chemotherapy, Cancer Center of Guangzhou Medical University Guangzhou, 510095, China.
Li-Ren HuDepartment of Epidemiology and Health Statistics, School of Public Health, Guangdong Medical College Zhanjiang, 524023, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumor suppressor in lung cancer 1 (TSLC1) is a novel tumor suppressor gene whose inactivation is implicated in the occurrence, invasion, metastasis and prognosis of esophageal cancer. TSLC1 was studied by comparing the tumor formation of TSLC1 transfectant and control cells in nude mice. Compared with blank group and mock group, tumor size and infiltrating range of transfected group was less, differentiation of tumor tissue was slightly better, and differences of tumor angiogenesis was worse. There was no obvious difference between blank group and mock group. We have shown TSLC1 gene inhibited the growth proliferation, infiltration and angiogenesis of Eca109 cells.

Indexed as

esophageal cancernude micetumorigenicityTumor suppressor genetumor suppressor in lung cancer -1 (TSLC1)

Identifiers

PMID25035773
PMCPMC4100959

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.