Evidence map›Paper›PMID 25035577›Full record

ReviewJournal of toxicologic pathology2013

Proliferative and non-proliferative lesions of the rat and mouse integument.

Lars Mecklenburg, Donna Kusewitt, Carine Kolly, Silke Treumann, E Terence Adams, Kelly Diegel, Jyoji Yamate, Wolfgang Kaufmann, Susanne Müller, Dimitry Danilenko and 1 more

Abstract readReview
In one paragraph

Review in Journal of toxicologic pathology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Article
  2. Article
  3. Melanomas (amelanotic type) in albino rats.Journal of toxicologic pathology · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Short-term Housing in Metabolic Caging on Measures of Energy and Fluid Balance in Male C57BL/6J Mice (Journal of the American Association for Laboratory Animal Science : JAALAS · 2022
    Article
  15. Review
  16. Evaluation of Treatment Options for Ulcerative Dermatitis in the P Rat.Journal of the American Association for Laboratory Animal Science : JAALAS · 2021
    Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lars Mecklenburgmecklenburg-consulting, Hamburg, Germany.
Donna KusewittUT MD Anderson Cancer Center, Smithville, Texas, USA.
Carine KollyNovartis Pharma AG, Basel, Switzerland.
Silke TreumannBASF SE, Ludwigshafen, Germany.
E Terence AdamsExperimental Pathology Laboratories, Inc, Research Triangle Park, North Carolina, USA.
Kelly DiegelHoffmann La-Roche Nonclinical Safety, Nutley, New Jersey, USA.
Jyoji YamateOsaka Prefecture University, Osaka, Japan.
Wolfgang KaufmannMerck Serono Research & Development, Darmstadt, Germany.
Susanne MüllerBoehringer Ingelheim Pharma GmbH & Co. KG, Biberach, Germany.
Dimitry DanilenkoGenentech, South San Francisco, California, USA.
Alys BradleyCharles River, Tranent, Edinburgh, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The INHAND (International Harmonization of Nomenclature and Diagnostic Criteria for Lesions in Rats and Mice) project is a joint initiative of the societies of toxicological pathology from Europe (ESTP), Great Britain (BSTP), Japan (JSTP) and North America (STP). Its aim is to develop an internationally-accepted nomenclature for proliferative and non-proliferative lesions in laboratory rodents. A widely accepted international harmonization of nomenclature in laboratory animals will decrease confusion among regulatory and scientific research organizations in different countries and will provide a common language to increase and enrich international exchanges of information among toxicologists and pathologists. The purpose of this publication is to provide a standardized nomenclature for classifying microscopical lesions observed in the integument of laboratory rats and mice. Example colour images are provided for most lesions. The standardized nomenclature presented in this document and additional colour images are also available electronically at http://www.goreni.org. The nomenclature presented herein is based on histopathology databases from government, academia, and industrial laboratories throughout the world, and covers lesions that develop spontaneously as well as those induced by exposure to various test materials. (DOI: 10.1293/tox.26.27S; J Toxicol Pathol 2013; 26: 27S-57S).

Indexed as

diagnostic pathologyhistopathologyintegumentary systemnomenclaturerodent pathologyskin; rodent

Identifiers

PMID25035577
PMCPMC4091526

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.