Evidence map›Paper›PMID 25035576›Full record

ReviewJournal of toxicologic pathology2013

Proliferative and non-proliferative lesions of the rat and mouse soft tissue, skeletal muscle and mesothelium.

Peter Greaves, Luc Chouinard, Heinrich Ernst, Lars Mecklenburg, Ingrid M Pruimboom-Brees, Matthias Rinke, Susanne Rittinghausen, Stéphane Thibault, Jasmin Von Erichsen, Toshinori Yoshida

Open access · bronzeAbstract readReview
In one paragraph

Review in Journal of toxicologic pathology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 76 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 5 countries.

Peter GreavesUniversity of Leicester, Department of Cancer Studies, Leicester, UK.
Luc ChouinardCharles River Laboratories, Quebec, Canada.
Heinrich ErnstFraunhofer Institute for Toxicology and Experimental Medicine ITEM, Hannover, Germany.
Lars MecklenburgEuropean Advanced Risk Assessor, Hamburg, Germany.
Ingrid M Pruimboom-BreesNovartis Pharma AG, Basel, Switzerland.
Matthias RinkeBayer Pharma AG, Wuppertal, Germany.
Susanne RittinghausenFraunhofer Institute for Toxicology and Experimental Medicine ITEM, Hannover, Germany.
Stéphane ThibaultPfizer Inc, California, USA.
Jasmin Von ErichsenNycomed: a Takeda Company, Barsbuettel, Germany.
Toshinori YoshidaThe Institute of Environmental Toxicology, Ibaraki, Japan.
Fraunhofer Institute for Toxicology and Experimental Medicine · DEBayer (Germany) · DECanadian Nuclear Laboratories · CANovartis (Switzerland) · CHPfizer (United States) · USSociety of Environmental Toxicology and Chemistry · USTakeda (Germany) · DEUniversity of Leicester · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The INHAND Project (International Harmonization of Nomenclature and Diagnostic Criteria for Lesions in Rats and Mice) is a joint initiative of the Societies of Toxicologic Pathology from Europe (ESTP), Great Britain (BSTP), Japan (JSTP), and North America (STP) to develop an internationally accepted nomenclature for proliferative and nonproliferative lesions in laboratory animals. The purpose of this publication is to provide a standardized nomenclature for classifying lesions observed in the soft tissues including skeletal muscle as well as the mesothelium of rats and mice. The standardized nomenclature of lesions presented in this document is also available electronically on the Internet (http://www.goreni.org/). Sources of material included histopathology databases from government, academia, and industrial laboratories throughout the world. Content includes spontaneous developmental and aging lesions as well as those induced by exposure to test materials. A widely accepted and utilized international harmonization of nomenclature for lesions in soft tissues, skeletal muscle and mesothelium in laboratory animals will decrease confusion among regulatory and scientific research organizations in different countries and provide a common language to increase and enrich international exchanges of information among toxicologists and pathologists. (DOI: 10.1293/tox.26.1S; J Toxicol Pathol 2013; 26: 1S-26S).

Indexed as

mesotheiummouse pathologypreclinical safety—assessment/risk managementrat pathologyskeletal musclessoft tissues

Identifiers

PMID25035576
PMCPMC4091527
OpenAlexW2020523402

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.