Evidence map›Paper›PMID 25034903›Full record

ArticleJournal of neurointerventional surgery2015

Treatment results of endosaccular coil embolization of asymptomatic unruptured intracranial aneurysms in elderly patients.

Hidenori Oishi, Munetaka Yamamoto, Senshu Nonaka, Takashi Shimizu, Kensaku Yoshida, Takashi Mitsuhashi, Hajime Arai

Abstract read
In one paragraph

Article in Journal of neurointerventional surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Increased Risk of Aortic Dissection with Perlecan Deficiency.International journal of molecular sciences · 2021
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hidenori OishiDepartment of Neuroendovascular Therapy, Juntendo University School of Medicine, Tokyo, Japan.
Munetaka YamamotoDepartment of Neurosurgery, Juntendo University School of Medicine, Tokyo, Japan.
Senshu NonakaDepartment of Neurosurgery, Juntendo Urayasu Hospital, Tokyo, Japan.
Takashi ShimizuDepartment of Neurosurgery, Juntendo Nerima Hospital, Tokyo, Japan.
Kensaku YoshidaDepartment of Neurosurgery, Tokyo Metropolitan Hiroo Hospital, Tokyo, Japan.
Takashi MitsuhashiDepartment of Neurosurgery, Tama-Nanbu Chiiki Hospital, Tokyo, Japan.
Hajime AraiDepartment of Neurosurgery, Juntendo University School of Medicine, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeWe report the results of endosaccular coil embolization of asymptomatic unruptured intracranial aneurysms (UIAs) in elderly patients (≥65 years). MATERIALS: There were 375 elderly patients with 400 asymptomatic UIAs. Patients were divided into two groups: group A included patients aged 65-74 years and group B patients aged ≥75 years.

resultsEndovascular procedures were completed in 97.8% of patients. Immediate anatomical outcomes showed complete occlusion in 53.7%, residual neck in 18.9%, and residual aneurysm in 27.4%. Anatomical follow-ups (mean 36.3±28.1 months) were unchanged in 55.7%, improved in 22.6%, minor recurrence in 11.5%, and major recurrence in 10.2%. Procedure related complications occurred in 31 patients (8.3%). 15 patients had ischemic and 10 hemorrhagic complications. Retreatments were performed in 16 patients (4.3%). Among 366 patients technically completed, 363 (99.2%) showed a favorable clinical outcome (modified Rankin Scale (mRS) score <1) at 30 days. The remaining three patients showed a worsening of mRS >0 at 30 days. The latest clinical follow-up outcomes showed: mRS score 0 in 362 patients; mRS score 1 in one; mRS score 3 in one; mRS score 4 in one; and mRS score 5 in one patient. Permanent morbidity and mortality rates were 1.1% and 0%, respectively. There were no statistically significant differences in gender, comorbidities, aneurysm size, neck width, dome-to-neck ratio, immediate anatomical outcomes, anatomical follow-up outcomes, or procedure related complications between the groups.

conclusionsEndosaccular coil embolization is safe and feasible for elderly patients with asymptomatic UIAs. Old age itself should not be a contraindication.

Indexed as

AgedAged, 80 and overAge FactorsAsymptomatic DiseasesEmbolization, TherapeuticFemaleHumansIntracranial AneurysmMaleTreatment OutcomeAneurysmIntervention

Identifiers

PMID25034903
PMCPMC4552889

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.