Evidence map›Paper›PMID 25034632›Full record

Trial reportBMJ open2014

A randomised controlled trial to compare the clinical and cost-effectiveness of prism glasses, visual search training and standard care in patients with hemianopia following stroke: a protocol.

F J Rowe, P G Barton, E Bedson, R Breen, E J Conroy, E Cwiklinski, C Dodridge, A Drummond, M Garcia-Finana, C Howard and 8 more

Open access · goldAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in BMJ open, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 3 pooled it
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 3 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Interventions for visual field defects in people with stroke.The Cochrane database of systematic reviews · 2019
    Pooled it
  3. Pooled it
  4. Trial
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 11 institutions in 1 country.

F J RoweDepartment of Health Services Research, University of Liverpool, Liverpool, UK.
P G BartonDepartment of Elderly Care, Warrington and Halton Hospitals NHS Foundation Trust, Warrington, UK.
E BedsonClinical Trials Research Unit, University of Liverpool, Liverpool, UK.
R BreenClinical Trials Research Unit, University of Liverpool, Liverpool, UK.
E J ConroyDepartment of Biostatistics, University of Liverpool, Liverpool, UK.
E CwiklinskiClinical Trials Research Unit, University of Liverpool, Liverpool, UK.
C DodridgeDepartment of Orthoptics, Oxford University Hospitals NHS Trust, Oxford, UK.
A DrummondSchool of Health Sciences, University of Nottingham, Nottingham, UK.
M Garcia-FinanaDepartment of Biostatistics, University of Liverpool, Liverpool, UK.
C HowardDepartment of Orthoptics, Salford Royal NHS Foundation Trust, Manchester, UK.
S JohnsonEye Clinic Impact Team, Royal National Institute for the Blind, Birmingham, UK.
C MacIntoshDepartment of Orthoptics, Oxford University Hospitals NHS Trust, Oxford, UK.
C P NoonanDepartment of Ophthalmology, Aintree University Hospital NHS Foundation Trust, Liverpool, UK.
A PollockNursing, Midwifery and Allied Health Professions Research Unit, Glasgow Caledonian University, Glasgow, UK.
J RockliffeSpeakability North West, London, UK.
C SackleyFaculty of Medicine and Health, University of East Anglia, Norwich, UK.
T ShipmanDepartment of Orthoptics, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.
VISION (vision impairment in stroke: intervention or not)
University of Liverpool · GBOxford University Hospitals NHS Trust · GBAintree University Hospitals NHS Foundation Trust · GBGlasgow Caledonian University · GBNorth West London Pathology · GBRoyal National Institute of Blind · GBSalford Royal NHS Foundation Trust · GBSheffield Teaching Hospitals NHS Foundation Trust · GBUniversity of East Anglia · GBUniversity of Nottingham · GBWarrington and Halton Teaching Hospitals NHS Foundation Trust · GB

Funding

Chief Scientist Office NMAHP2Department of Health CDF-2012-05-126
6 · The paper itself

Abstract

introductionHomonymous hemianopia is a common and disabling visual problem after stroke. Currently, prism glasses and visual scanning training are proposed to improve it. The aim of this trial is to determine the effectiveness of these interventions compared to standard care. METHODS AND ANALYSIS: The trial will be a multicentre three arm individually randomised controlled trial with independent assessment at 6 week, 12 week and 26 week post-randomisation. Recruitment will occur in hospital, outpatient and primary care settings in UK hospital trusts. A total of 105 patients with homonymous hemianopia and without ocular motility impairment, visual inattention or pre-existent visual field impairment will be randomised to one of three balanced groups. Randomisation lists will be stratified by site and hemianopia level (partial or complete) and created using simple block randomisation by an independent statistician. Allocations will be disclosed to patients by the treating clinician, maintaining blinding for outcome assessment. The primary outcome will be change in visual field assessment from baseline to 26 weeks. Secondary measures will include the Rivermead Mobility Index, Visual Function Questionnaire 25/10, Nottingham Extended Activities of Daily Living, Euro Qual-5D and Short Form-12 questionnaires. Analysis will be by intention to treat. ETHICS AND DISSEMINATION: This study has been developed and supported by the UK Stroke Research Network Clinical Studies Group working with service users. Multicentre ethical approval was obtained through the North West 6 Research ethics committee (Reference 10/H1003/119). The trial is funded by the UK Stroke Association. Trial Registration: Current Controlled Trials ISRCTN05956042. Dissemination will consider usual scholarly options of conference presentation and journal publication in addition to patient and public dissemination with lay summaries and articles.

trial registrationCurrent Controlled Trials ISRCTN05956042.

Indexed as

EyeglassesCost-Benefit AnalysisEquipment DesignHemianopsiaHumansResearch DesignSingle-Blind MethodStrokeSurveys and QuestionnairesTreatment OutcomeREHABILITATION MEDICINESTROKE MEDICINE

Identifiers

PMID25034632
PMCPMC4120412
OpenAlexW2109562021

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.