ArticleThe European respiratory journal2014
The PROactive innovative conceptual framework on physical activity.
Article in The European respiratory journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03042806 (Validation of a Questionnaire Evaluating the Physical Activities in COPD Patients), which is not on this map. Cited by 30 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Validation of a Questionnaire Evaluating the Physical Activities in COPD Patients: the Maugeri Physical Activity Questionnaire - MaPAct
Who cites it
30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 69 citations in OpenAlex.
- Identifying Concepts of Physical Activity Which Are Clinically Meaningful to Patients and Care Providers: A Systematic Review of Qualitative Research.Clinical and translational science · 2025Pooled it
- Listening to the patients' voice: a conceptual framework of the walking experience.Age and ageing · 2023Pooled it
- Trial
- The PROactive instruments to measure physical activity in patients with chronic obstructive pulmonary disease.The European respiratory journal · 2015Trial
- A Metasynthesis of Qualitative Literature to Inform the Selection of Meaningful and Measurable Health Concepts for Clinical Trials in COPD.Chronic obstructive pulmonary diseases (Miami, Fla.) · 2025Article
- Qualitative interviews of patients with COPD and muscle weakness enrolled in a clinical trial evaluating a new anabolic treatment: patient perspectives of disease experience, trial participation and outcome assessments.Journal of patient-reported outcomes · 2024Article
- Real-world walking cadence in people with COPD.ERJ open research · 2024Article
- Nutritional Support and Physical Activity Intervention Programs with a Person-Centred Approach in People with Chronic Obstructive Pulmonary Disease: a Scoping Review.International journal of chronic obstructive pulmonary disease · 2024Article
- Cognitive behavioural therapy combined with physical activity behavioural modification strategies during pulmonary rehabilitation in patients with COPD.ERJ open research · 2023Article
- Cultural adaptation and validation of the Brazilian Portuguese version of the PROactive Physical Activity in COPD-clinical visit instrument for individuals with COPD.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2023Article
- Editorial: Exercise intervention for prevention, management of and rehabilitation from chronic obstructive pulmonary disease (COPD).Frontiers in physiology · 2023Article
- A Conceptual Framework for Use of Increased Endurance Time During Constant Work Rate Cycle Ergometry as a Patient-Focused Meaningful Outcome in COPD Clinical Trials.Chronic obstructive pulmonary diseases (Miami, Fla.) · 2022Review
- Article
- Validation of the Spanish Activity Questionnaire in COPD (SAQ-COPD) in Patients with Chronic Obstructive Pulmonary Disease.International journal of chronic obstructive pulmonary disease · 2022Article
- Objectively Measured Physical Activity in Patients with COPD: Recommendations from an International Task Force on Physical Activity.Chronic obstructive pulmonary diseases (Miami, Fla.) · 2021Article
- Walking on common ground: a cross-disciplinary scoping review on the clinical utility of digital mobility outcomes.NPJ digital medicine · 2021Article
- Article
- A machine learning approach to predict extreme inactivity in COPD patients using non-activity-related clinical data.PloS one · 2021Article
- The Influence of Pulmonary Rehabilitation and Counselling on Perceptions of Physical Activity in Individuals with COPD - A Qualitative Study.International journal of chronic obstructive pulmonary disease · 2021Article
- Walking-related digital mobility outcomes as clinical trial endpoint measures: protocol for a scoping review.BMJ open · 2020Article
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Authors and funding
19 authors at 10 institutions in 7 countries.
Funding
Abstract
Although physical activity is considered an important therapeutic target in chronic obstructive pulmonary disease (COPD), what "physical activity" means to COPD patients and how their perspective is best measured is poorly understood. We designed a conceptual framework, guiding the development and content validation of two patient reported outcome (PRO) instruments on physical activity (PROactive PRO instruments). 116 patients from four European countries with diverse demographics and COPD phenotypes participated in three consecutive qualitative studies (63% male, age mean±sd 66±9 years, 35% Global Initiative for Chronic Obstructive Lung Disease stage III-IV). 23 interviews and eight focus groups (n = 54) identified the main themes and candidate items of the framework. 39 cognitive debriefings allowed the clarity of the items and instructions to be optimised. Three themes emerged, i.e. impact of COPD on amount of physical activity, symptoms experienced during physical activity, and adaptations made to facilitate physical activity. The themes were similar irrespective of country, demographic or disease characteristics. Iterative rounds of appraisal and refinement of candidate items resulted in 30 items with a daily recall period and 34 items with a 7-day recall period. For the first time, our approach provides comprehensive insight on physical activity from the COPD patients' perspective. The PROactive PRO instruments' content validity represents the pivotal basis for empirically based item reduction and validation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.