ArticlePediatric nephrology (Berlin, Germany)2014
Increased risk of idiopathic nephrotic syndrome in children with atopic dermatitis.
Article in Pediatric nephrology (Berlin, Germany), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 40 citations in OpenAlex.
- The application of omalizumab in children with atopic diseases complicated by nephrotic syndrome: a case report.CEN case reports · 2025Article
- Causal relationship between inflammatory skin diseases and immunoglobulin A nephropathy: A Mendelian randomization and enrichment analysis study.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024Article
- Nephrotic syndrome with Minimal Change Disease and Atopy in NorthAfrican adults.La Tunisie medicale · 2023Observational
- An updated view of the pathogenesis of steroid-sensitive nephrotic syndrome.Pediatric nephrology (Berlin, Germany) · 2022Review
- Association between gaseous air pollutants and idiopathic nephrotic syndrome in children: a 12-year population-based cohort study.Italian journal of pediatrics · 2022Article
- The immunopathogenesis of idiopathic nephrotic syndrome: a narrative review of the literature.European journal of pediatrics · 2022Review
- Case Report: The Application of Dupilumab in Atopic Dermatitis Children Complicated With Nephrotic Syndrome.Frontiers in medicine · 2022Article
- Inflammatory skin diseases and the risk of chronic kidney disease: population-based case-control and cohort analyses.The British journal of dermatology · 2021Article
- Atopic eczema in adulthood and mortality: UK population-based cohort study, 1998-2016.The Journal of allergy and clinical immunology · 2021Article
- A review of nephrotic syndrome and atopic diseases in children.Translational andrology and urology · 2021Review
- Long-term risk of pneumothorax in asthmatic children: A 12-year population-based cohort study.Medicine · 2020Article
- Synaptopodin is upregulated by IL-13 in eosinophilic esophagitis and regulates esophageal epithelial cell motility and barrier integrity.JCI insight · 2017Article
- Correlation Between Idiopathic Nephrotic Syndrome and Atopy in Children - Short Review.Maedica · 2017Article
- Article
- Epidemiology and risk of juvenile idiopathic arthritis among children with allergic diseases: a nationwide population-based study.Pediatric rheumatology online journal · 2016Article
- Article
- Risk of Nephrotic Syndrome following Enteroviral Infection in Children: A Nationwide Retrospective Cohort Study.PloS one · 2016Article
- Neonatal jaundice and risks of childhood allergic diseases: a population-based cohort study.Pediatric research · 2015Article
- Occurrence of common allergic diseases in children with idiopathic nephrotic syndrome.Journal of epidemiology · 2015Article
- Atopic Dermatitis: Clinical Connotations, Especially a Focus on Concomitant Atopic Undertones in Immunocompromised/Susceptible Genetic and Metabolic Disorders.Indian journal of dermatologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundClinical and immunological studies have consistently shown a relationship between atopic diathesis and idiopathic nephrotic syndrome (INS). However, no large population cohort study has yet to demonstrate the nature of the relationship between these disorders.
methodsClaims data from a random selection of children representing half of the insured population in Taiwan were examined. During the period from 1998 to 2007, we identified 192,295 children aged <18 years with newly diagnosed atopic dermatitis (AD) and 769,169 frequency-matched controls. Incidence of INS and hazard ratios (HRs) were calculated.
resultsThe AD cohort had a 2-fold higher overall incidence of INS than the non-AD cohort [7.20 vs. 3.60 per 100,000 person-years, respectively; 95 % confidence interval (CI) 1.50-2.66]. The HR for INS increased with age and was higher among females. The HR for INS was also higher in AD children with more medical visits per year, ranging from 0.94 for those having ≤3 visits to 38.6 for those having >6 visits (trend test P < 0.0001). In particular, the risk of INS clearly increased during the initial 5 years after AD onset.
conclusionsChildren with AD have a greater incidence and risk of developing INS and this risk increases with AD severity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.