Evidence map›Paper›PMID 25034161›Full record

ArticleRheumatic diseases clinics of North America2014

The kidney biopsy in lupus nephritis: is it still relevant?

Brad H Rovin, Samir V Parikh, Anthony Alvarado

Open access · greenAbstract read
In one paragraph

Article in Rheumatic diseases clinics of North America, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
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  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. [Lupus nephritis].Zeitschrift fur Rheumatologie · 2018
    Article
  14. Article
  15. Histologic versus clinical remission in proliferative lupus nephritis.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2017
    Article
  16. Review
  17. Review
  18. Long-term Outcome of Lupus Nephritis Class II in Argentine Patients: An Open Retrospective Analysis.Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases · 2016
    Article
  19. What is damaging the kidney in lupus nephritis?Nature reviews. Rheumatology · 2016
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Brad H RovinNephrology Division, Department of Internal Medicine, Ohio State University Wexner Medical Center, 395 West 12th Avenue, Columbus, OH 43210, USA. Electronic address: rovin.1@osu.edu.
Samir V ParikhNephrology Division, Department of Internal Medicine, Ohio State University Wexner Medical Center, 395 West 12th Avenue, Columbus, OH 43210, USA.
Anthony AlvaradoNephrology Division, Department of Internal Medicine, Ohio State University Wexner Medical Center, 395 West 12th Avenue, Columbus, OH 43210, USA.
The Ohio State University · US

Funding

Discovery & Validation of Biomarkers of Kidney PathologyU01DK096927 · NIDDK · OHIO STATE UNIVERSITY · PI ROVIN, BRAD H · 2013 to 2017
$2.0M
NIDDK NIH HHS U01 DK096927
6 · The paper itself

Abstract

The kidney biopsy is the standard of care for diagnosis of lupus nephritis and remains necessary to ensure accurate diagnosis and guide treatment. Repeat biopsy should be considered when therapy modifications are necessary, as in cases with incomplete or no response, or when stopping therapy for those in remission. There are several promising biomarkers of kidney disorders; however, these markers need to be validated in a prospective clinical trial before being applied clinically. Molecular analysis may provide the information presently lacking from current evaluation of kidney disorders and may better inform on prognosis and treatment considerations.

Indexed as

Lupus NephritisAlgorithmsBiomarkersBiopsyComparative Effectiveness ResearchDisease ManagementDrug MonitoringHumansKidneyPrognosisReproducibility of ResultsStandard of CareBiomarkersKidney biopsyLupus nephritisSystemic lupus erythematosus

Identifiers

PMID25034161
PMCPMC4145529
OpenAlexW132645494

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.