ArticleScientific reports2014
Diet-dependent gene expression in honey bees: honey vs. sucrose or high fructose corn syrup.
Article in Scientific reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
35 citing papers in PubMed, 92 citations in OpenAlex.
- Integrated Assessment of Pollen Substitute Diets in Honey Bees Based on Transcriptional Responses, Immune-Derived Predicted Biological Age, and Survival.Animals : an open access journal from MDPI · 2026Article
- Diet Quality Shapes Metabolic and Immune Transcriptional Responses of Honey Bees Under Acute Heat Stress.Insects · 2026Article
- Glycosidase Isoforms in Honey and the Honey Bee (Insects · 2025Article
- Molecular Assessment of Genes Linked to Honeybee Health Fed with Different Diets in Nuclear Colonies.Insects · 2025Article
- Review
- A novel Fish Protein Hydrolysate supplement enhances honey bee foraging activity and colony strength: A pilot study.PloS one · 2025Article
- Honey bee colony losses and causes during the active beekeeping season 2022/2023 in nine Sub-Saharan African countries.PloS one · 2025Article
- Composition and Quality of Honey Bee Feed: The Methodology and Monitoring of Candy Boards.Animals : an open access journal from MDPI · 2024Article
- The Therapeutic Mechanisms of Honey in Mitigating Toxicity from Anticancer Chemotherapy Toxicity: A Review.Journal of xenobiotics · 2024Review
- Evaluation of Functional Properties of Some Lactic Acid Bacteria Strains for Probiotic Applications in Apiculture.Microorganisms · 2024Article
- Effect of various supplements on productive performance of honey bees, in the south Wollo Zone, Ethiopia.PloS one · 2024Article
- Carbohydrate nutrition associated with health of overwintering honey bees.Journal of insect science (Online) · 2023Article
- Article
- Article
- Effects of the Carbohydrate Sources Nectar, Sucrose and Invert Sugar on Antibacterial Activity of Honey and Bee-Processed Syrups.Antibiotics (Basel, Switzerland) · 2021Article
- Polyphenols as Food Supplement Improved Food Consumption and Longevity of Honey Bees (Insects · 2021Article
- Influence of formic acid treatment on the proteome of the ectoparasite Varroa destructor.PloS one · 2021Article
- Improving bee health through genomics.Nature reviews. Genetics · 2020Review
- The transcriptomic signature of low aggression in honey bees resembles a response to infection.BMC genomics · 2019Article
- Towards Precision Nutrition: A Novel Concept Linking Phytochemicals, Immune Response and Honey Bee Health.Insects · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Severe declines in honey bee populations have made it imperative to understand key factors impacting honey bee health. Of major concern is nutrition, as malnutrition in honey bees is associated with immune system impairment and increased pesticide susceptibility. Beekeepers often feed high fructose corn syrup (HFCS) or sucrose after harvesting honey or during periods of nectar dearth. We report that, relative to honey, chronic feeding of either of these two alternative carbohydrate sources elicited hundreds of differences in gene expression in the fat body, a peripheral nutrient-sensing tissue analogous to vertebrate liver and adipose tissues. These expression differences included genes involved in protein metabolism and oxidation-reduction, including some involved in tyrosine and phenylalanine metabolism. Differences between HFCS and sucrose diets were much more subtle and included a few genes involved in carbohydrate and lipid metabolism. Our results suggest that bees receive nutritional components from honey that are not provided by alternative food sources widely used in apiculture.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.