ArticleLa Radiologia medica2015
Parotid glands in whole-brain radiotherapy: 2D versus 3D technique for no sparing or sparing.
Article in La Radiologia medica, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Organs in plain sight-parotid gland doses in short-course palliative whole-brain radiotherapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Article
- Examination of the best head tilt angle to reduce the parotid gland dose maintaining a safe level of lens dose in whole-brain radiotherapy using the four-field box technique.Journal of applied clinical medical physics · 2021Article
- Whole brain radiotherapy using four-field box technique with tilting baseplate for parotid gland sparing.Radiation oncology journal · 2019Article
- Assessment of Risk of Xerostomia After Whole-Brain Radiation Therapy and Association With Parotid Dose.JAMA oncology · 2019Observational
- Non-coplanar whole brain radiotherapy is an effective modality for parotid sparing.Yeungnam University journal of medicine · 2019Article
- Evaluation of Effective Parameters on Quality of Magnetic Resonance Imaging-computed Tomography Image Fusion in Head and Neck Tumors for Application in Treatment Planning.Advanced biomedical research · 2017Article
- Potential for reduced radiation-induced toxicity using intensity-modulated arc therapy for whole-brain radiotherapy with hippocampal sparing.Journal of applied clinical medical physics · 2015Article
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Authors and funding
8 authors.
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No grant is acknowledged in the PubMed record.
Abstract
purposeWhole-brain radiotherapy is performed as standard therapy in patients with multiple brain metastases and in patients with more favourable prognosis such as lymphoma and small-cell lung carcinoma in the prophylactic setting. Because of the prognosis and the total prescribed dose, the parotid glands are not usually regarded as an organ at risk in whole-brain radiotherapy. Long-term survival can be expected in some of these patients and late toxicity can be observed, becoming essential to evaluate organs at risk, particularly the parotid glands even in metastatic patients. We compared the 2D with 3D technique to evaluate parotid glands involvement and received dose, and coverage of the clinical target volume. MATERIALS AND
methodsSeven patients were considered. The prescribed dose was 30 Gy in ten fractions. On the same day and with the same set-up, all the treatment planning were performed using a 2D and 3D technique. A treatment plan was performed following same technical characteristics as the 2D technique. The parotid glands and whole brain were delineated. Dose-volume statistics were analysed.
resultsDose-volume histograms of the parotid glands showed that 2/7 patients (28 %) received a mean dose >20 Gy. We found a lack of coverage of the clinical target volume in 6/7 patients.
conclusionsPlanning whole-brain radiotherapy with only the 2D technique involves a risk of including parotid glands in the field and not covering the clinical target volume. The 3D technique should be systematically performed and the parotid glands should be regarded as an organ at risk in whole-brain radiotherapy.
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