ArticlePloS one2014
Shift in the microbial ecology of a hospital hot water system following the introduction of an on-site monochloramine disinfection system.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed.
- Review
- Ten questions concerning water quality in building hot water systems.Building and environment · 2025Article
- Review
- Influence of pipe materials on in-building disinfection ofWater research X · 2023Article
- Seasonality of healthcare-associatedInfection control and hospital epidemiology · 2023Article
- Article
- A comprehensive evaluation of monochloramine disinfection on water quality, Legionella and other important microorganisms in a hospital.Water research · 2021Article
- Evaluation of DNA extraction yield from a chlorinated drinking water distribution system.PloS one · 2021Article
- Critical Review: Propensity of Premise Plumbing Pipe Materials to Enhance or Diminish Growth ofPathogens (Basel, Switzerland) · 2020Review
- Disinfectant, Soap or Probiotic Cleaning? Surface Microbiome Diversity and Biofilm Competitive Exclusion.Microorganisms · 2020Article
- Characterisation of Microbial Community Associated with Different Disinfection Treatments in Hospital hot Water Networks.International journal of environmental research and public health · 2020Article
- Article
- Article
- Nontuberculous mycobacteria in drinking water systems - the challenges of characterization and risk mitigation.Current opinion in biotechnology · 2019Review
- OTUX: V-region specific OTU database for improved 16S rRNA OTU picking and efficient cross-study taxonomic comparison of microbiomes.DNA research : an international journal for rapid publication of reports on genes and genomes · 2019Article
- Article
- Recreational Use of Spa Thermal Waters: Criticisms and Perspectives for Innovative Treatments.International journal of environmental research and public health · 2018Review
- Shotgun Metagenomics Reveals Taxonomic and Functional Shifts in Hot Water Microbiome Due to Temperature Setting and Stagnation.Frontiers in microbiology · 2018Article
- Interactive effects of temperature, organic carbon, and pipe material on microbiota composition and Legionella pneumophila in hot water plumbing systems.Microbiome · 2017Article
- Communicating the promise, risks, and ethics of large-scale, open space microbiome and metagenome research.Microbiome · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Drinking water distribution systems, including premise plumbing, contain a diverse microbiological community that may include opportunistic pathogens. On-site supplemental disinfection systems have been proposed as a control method for opportunistic pathogens in premise plumbing. The majority of on-site disinfection systems to date have been installed in hospitals due to the high concentration of opportunistic pathogen susceptible occupants. The installation of on-site supplemental disinfection systems in hospitals allows for evaluation of the impact of on-site disinfection systems on drinking water system microbial ecology prior to widespread application. This study evaluated the impact of supplemental monochloramine on the microbial ecology of a hospital's hot water system. Samples were taken three months and immediately prior to monochloramine treatment and monthly for the first six months of treatment, and all samples were subjected to high throughput Illumina 16S rRNA region sequencing. The microbial community composition of monochloramine treated samples was dramatically different than the baseline months. There was an immediate shift towards decreased relative abundance of Betaproteobacteria, and increased relative abundance of Firmicutes, Alphaproteobacteria, Gammaproteobacteria, Cyanobacteria and Actinobacteria. Following treatment, microbial populations grouped by sampling location rather than sampling time. Over the course of treatment the relative abundance of certain genera containing opportunistic pathogens and genera containing denitrifying bacteria increased. The results demonstrate the driving influence of supplemental disinfection on premise plumbing microbial ecology and suggest the value of further investigation into the overall effects of premise plumbing disinfection strategies on microbial ecology and not solely specific target microorganisms.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.