Evidence map›Paper›PMID 25033215›Full record

ReviewPLoS pathogens2014

Defensins and viral infection: dispelling common misconceptions.

Mayim E Wiens, Sarah S Wilson, Carissa M Lucero, Jason G Smith

Abstract readReview
In one paragraph

Review in PLoS pathogens, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Antiviral Activities of Human Host Defense Peptides.Current medicinal chemistry · 2020
    Review
  3. Review
  4. Review
  5. Article
  6. Guardians of the Gut: Enteric Defensins.Frontiers in microbiology · 2017
    Review
  7. Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mayim E WiensDepartment of Microbiology, University of Washington, Seattle, Washington, United States of America.
Sarah S WilsonDepartment of Microbiology, University of Washington, Seattle, Washington, United States of America.
Carissa M LuceroDepartment of Microbiology, University of Washington, Seattle, Washington, United States of America.
Jason G SmithDepartment of Microbiology, University of Washington, Seattle, Washington, United States of America.

Funding

TRAINING IN MOLECULAR AND CELLULAR BIOLOGYT32GM007270 · NIGMS · UNIVERSITY OF WASHINGTON · PI RAIBLE, DAVID W · 1985 to 2020
$21.0M
Anti-viral Mechanisms of DefensinsR01AI104920 · NIAID · UNIVERSITY OF WASHINGTON · PI MCKENNA, ROBERT, SMITH, JASON G · 2014 to 2023
$6.1M
Defensins in Innate Immunity to VirusesR56AI097311 · NIAID · UNIVERSITY OF WASHINGTON · PI SMITH, JASON G · 2012 to 2012
$299k
NIAID NIH HHS R01 AI104920NIAID NIH HHS R56 AI097311NIGMS NIH HHS T32 GM007270NIGMS NIH HHS T32 GM07270
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

alpha-DefensinsAnimalsbeta-DefensinsHumansVirus Diseasesalpha-Defensinsbeta-Defensins

Identifiers

PMID25033215
PMCPMC4102581

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.