Evidence map›Paper›PMID 25033145›Full record

ArticleAmerican journal of public health2014

Prevalence of undiagnosed acute and chronic HIV in a lower-prevalence urban emergency department.

Phillip C Moschella, Kimberly W Hart, Andrew H Ruffner, Christopher J Lindsell, D Beth Wayne, Matthew I Sperling, Alexander T Trott, Carl J Fichtenbaum, Michael S Lyons

Abstract read
In one paragraph

Article in American journal of public health, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Observational
  4. Article
  5. Thoracotomy in the emergency department for resuscitation of the mortally injured.Chinese journal of traumatology = Zhonghua chuang shang za zhi · 2017
    Article
  6. Real-world performance of the new US HIV testing algorithm in medical settings.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2017
    Article
  7. Prevalence of Diagnosed and Undiagnosed Hepatitis C in a Midwestern Urban Emergency Department.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2016
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Phillip C MoschellaPhillip C. Moschella, Kimberly W. Hart, Andrew H. Ruffner, Christopher J. Lindsell, D. Beth Wayne, Matthew I. Sperling, Alexander T. Trott, and Michael S. Lyons are with the Department of Emergency Medicine, University of Cincinnati College of Medicine, Cincinnati, OH. Carl J. Fichtenbaum is with the Division of Infectious Diseases, University of Cincinnati College of Medicine.
Kimberly W Hart
Andrew H Ruffner
Christopher J Lindsell
D Beth Wayne
Matthew I Sperling
Alexander T Trott
Carl J Fichtenbaum
Michael S Lyons

Funding

CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR026314 · NCRR · UNIVERSITY OF CINCINNATI · PI HEUBI, JAMES E. · 2009 to 2011
$14.3M
Cincinnati Center for Clinical and Translational Sciences and TrainingUL1TR000077 · NCATS · UNIVERSITY OF CINCINNATI · PI HEUBI, JAMES E. · 2012 to 2014
$9.9M
HIV Screening in the Emergency Department SettingK23AI068453 · NIAID · UNIVERSITY OF CINCINNATI · PI LYONS, MICHAEL S · 2006 to 2010
$668k
NCATS NIH HHS UL1 TR000077NCRR NIH HHS 5UL1RR026314NCRR NIH HHS UL1 RR026314NIAID NIH HHS K23 AI068453
6 · The paper itself

Abstract

objectivesWe estimated the seroprevalence of both acute and chronic HIV infection by using a random sample of emergency department (ED) patients from a region of the United States with low-to-moderate HIV prevalence.

methodsThis cross-sectional seroprevalence study consecutively enrolled patients aged 18 to 64 years within randomly selected sampling blocks in a Midwestern urban ED in a region of lower HIV prevalence in 2008 to 2009. Participants were compensated for providing a blood sample and health information. After de-identification, we assayed samples for HIV antibody and nucleic acid.

resultsThere were 926 participants who consented and enrolled. Overall, prevalence of undiagnosed HIV was 0.76% (95% confidence interval [CI] = 0.30%, 1.56%). Three participants (0.32%; 95% CI = 0.09%, 0.86%) were nucleic acid-positive but antibody-negative and 4 (0.43%; 95% CI = 0.15%, 1.02%) were antibody-positive.

conclusionsEven when the absolute prevalence is low, a considerable proportion of undetected HIV cases in an ED population are acute. Identification of acute HIV in ED settings should receive increased priority.

Indexed as

Acute DiseaseAdolescentAdultChronic DiseaseCross-Sectional StudiesEmergency Service, HospitalFemaleHIV AntibodiesHIV InfectionsHIV SeroprevalenceHospitals, UrbanHumansMaleMiddle AgedPrevalenceRisk FactorsHIV Antibodies

Identifiers

PMID25033145
PMCPMC4151950

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.