Evidence map›Paper›PMID 25033130›Full record

ArticleAmerican journal of public health2015

Characterization of dementia and Alzheimer's disease in an older population: updated incidence and life expectancy with and without dementia.

Sarah E Tom, Rebecca A Hubbard, Paul K Crane, Sebastien J Haneuse, James Bowen, Wayne C McCormick, Susan McCurry, Eric B Larson

Open access · greenAbstract read
In one paragraph

Article in American journal of public health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 88 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
88citing papers in PubMed, 2 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

88 citing papers in PubMed, 2 syntheses or guidelines pooled it, 179 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. A multidomain trial for cognition in women with cardiovascular disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Trial
  4. Trial
  5. The impact of hearing loss on annual incident age-associated dementia cases and quality of life in the United States.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026
    Article
  6. Article
  7. Sex Differences in Dementia and Mild Cognitive Impairment in Nondialysis CKD.Clinical journal of the American Society of Nephrology : CJASN · 2026
    Article
  8. Article
  9. Single-cell landscape of sex-specific drivers of Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. All-Cause Mortality and Cause-Specific Death in U.S. Long-Lived Siblings: Data From the Long Life Family Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024
    Article
  16. Article
  17. Article
  18. 2024 Alzheimer's disease facts and figures.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Article
  19. Article
  20. Article

28 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Sarah E TomSarah E. Tom is with the Pharmaceutical Health Services Research Department, School of Pharmacy, University of Maryland, Baltimore. Rebecca A. Hubbard and Eric B. Larson are with the Group Health Research Institute, Group Health Cooperative, Seattle, WA. Paul K. Crane and Eric B. Larson are with the Department of Medicine, University of Washington, Seattle. Sebastien J. Haneuse is with the Department of Biostatistics, School of Public Health, Harvard University, Cambridge, MA. James Bowen is with the Swedish Neuroscience Institute, Seattle, WA. Wayne C. McCormick is with the Harborview Medical Center, Seattle, WA. Susan McCurry is with Psychosocial and Community Health, School of Nursing, University of Washington.
Rebecca A Hubbard
Paul K Crane
Sebastien J Haneuse
James Bowen
Wayne C McCormick
Susan McCurry
Eric B Larson
University of Maryland, Baltimore · US

Funding

Furthering scientific understanding of mechanisms underlying resilience to the effects of AD pathology by incorporating state of the art quantification of gliosis, inflammation, & synaptic toxicityU01AG006781 · NIA · UNIVERSITY OF WASHINGTON · PI CRANE, PAUL K, LARSON, ERIC B · 1986 to 2020
$39.3M
UTMB WOMEN'S HEALTH RESEARCH SCHOLARS PROGRAMK12HD052023 · NICHD · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI BERENSON, ABBEY B · 2005 to 2023
$8.1M
Health Care Improvement for Aging WomenT32AG027677 · NIA · KAISER FOUNDATION HEALTH PLAN OF WASHINGTON · PI LACROIX, ANDREA Z. · 2007 to 2016
$1.4M
NIA NIH HHS AG 027677NIA NIH HHS AG 06781NIA NIH HHS T32 AG027677NIA NIH HHS U01 AG006781NICHD NIH HHS HD 052023NICHD NIH HHS K12 HD052023
6 · The paper itself

Abstract

objectivesWe estimated dementia incidence rates, life expectancies with and without dementia, and percentage of total life expectancy without dementia.

methodsWe studied 3605 members of Group Health (Seattle, WA) aged 65 years or older who did not have dementia at enrollment to the Adult Changes in Thought study between 1994 and 2008. We estimated incidence rates of Alzheimer's disease and dementia, as well as life expectancies with and without dementia, defined as the average number of years one is expected to live with and without dementia, and percentage of total life expectancy without dementia.

resultsDementia incidence increased through ages 85 to 89 years (74.2 cases per 1000 person-years) and 90 years or older (105 cases per 1000 person-years). Life expectancy without dementia and percentage of total life expectancy without dementia decreased with age. Life expectancy with dementia was longer in women and people with at least a college degree. Percentage of total life expectancy without dementia was greater in younger age groups, men, and those with more education.

conclusionsEfforts to delay onset of dementia, if successful, would likely benefit older adults of all ages.

Indexed as

Life ExpectancyAgedAged, 80 and overAge FactorsAlzheimer DiseaseDementiaEducational StatusFemaleHumansIncidenceMaleRisk FactorsSex FactorsWashington

Identifiers

PMID25033130
PMCPMC4318311
OpenAlexW2135591029

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.