ArticleCurrent opinion in microbiology2014
High-throughput sequencing for the study of bacterial pathogen biology.
Article in Current opinion in microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- Intestinal colonization of weaner pigs by extended-spectrum-β-lactamase-encoding Escherichia coli classified for differential host-association using a phylogenetics-based approach.Scientific reports · 2026Article
- Comparative genomics reveals key adaptive mechanisms in pathogen host-niche specialization.Frontiers in microbiology · 2025Article
- The effects of clays on bacterial community composition during arthropod decay.Swiss journal of palaeontology · 2024Article
- Coexistence ofEnvironmental science & technology · 2023Article
- Oropharyngeal, proximal colonic, and vaginal microbiomes of healthy Korean native black pig gilts.BMC microbiology · 2023Article
- Characterization ofFrontiers in microbiology · 2023Article
- The Innovative Informatics Approaches of High-Throughput Technologies in Livestock: Spearheading the Sustainability and Resiliency of Agrigenomics Research.Life (Basel, Switzerland) · 2022Review
- Forecasting Staphylococcus aureus Infections Using Genome-Wide Association Studies, Machine Learning, and Transcriptomic Approaches.mSystems · 2022Article
- Editorial: Genome-Wide Analyses ofFrontiers in plant science · 2022Article
- Detecting Genetic Variation of ColonizingFrontiers in bioinformatics · 2022Article
- Contaminant DNA in bacterial sequencing experiments is a major source of false genetic variability.BMC biology · 2020Article
- Genome-Wide Analyses Revealed Remarkable Heterogeneity in Pathogenicity Determinants, Antimicrobial Compounds, and CRISPR-Cas Systems of Complex Phytopathogenic GenusPathogens (Basel, Switzerland) · 2019Article
- Genome-wide identification ofProceedings of the National Academy of Sciences of the United States of America · 2019Article
- Changes in the genetic requirements for microbial interactions with increasing community complexity.eLife · 2018Article
- Standardization ofJournal of fungi (Basel, Switzerland) · 2018Review
- Population genomics of bacterial host adaptation.Nature reviews. Genetics · 2018Review
- MentaLiST - A fast MLST caller for large MLST schemes.Microbial genomics · 2018Article
- Comparative genomics of Burkholderia multivorans, a ubiquitous pathogen with a highly conserved genomic structure.PloS one · 2017Article
- An empirical strategy to detect bacterial transcript structure from directional RNA-seq transcriptome data.BMC genomics · 2015Article
- Cell scale host-pathogen modeling: another branch in the evolution of constraint-based methods.Frontiers in microbiology · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
A revolution in sequencing technologies in recent years has led to dramatically increased throughput and reduced cost of bacterial genome sequencing. An increasing number of applications of the new technologies are providing broad insights into bacterial evolution, epidemiology, and pathogenesis. For example, the capacity to sequence large numbers of bacterial isolates is enabling high resolution phylogenetic analyses of bacterial populations leading to greatly enhanced understanding of the emergence, adaptation, and transmission of pathogenic clones. In addition, RNA-seq offers improved quantification and resolution for transcriptomic analysis, and the combination of high-throughput sequencing with transposon mutagenesis is a powerful approach for the identification of bacterial determinants required for survival in vivo. In this concise review we provide selected examples of how high throughput sequencing is being applied to understand the biology of bacterial pathogens, and discuss future technological advances likely to have a profound impact on the field.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.