Trial reportPsychoneuroendocrinology2014
Interpersonal stressors predict ghrelin and leptin levels in women.
Trial report in Psychoneuroendocrinology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 50 citations in OpenAlex.
- Transcutaneous vagal nerve stimulation modulates stress-induced plasma ghrelin levels: A double-blind, randomized, sham-controlled trial.Journal of affective disorders · 2023Trial
- Loneliness predicts postprandial ghrelin and hunger in women.Hormones and behavior · 2015Trial
- Does Loneliness Hurt? Effect of Loneliness on Inflammator Biomarkers, Appetite Hormone Regulation, and Cognitive Function Among Typically Developing Adolescents.Journal of the Canadian Academy of Child and Adolescent Psychiatry = Journal de l'Academie canadienne de psychiatrie de l'enfant et de l'adolescent · 2025Article
- An Emerging Role for Gut-Brain Signaling Involving Ghrelin in Chronic Stress.Advances in experimental medicine and biology · 2025Review
- Psychoneuroimmunology and the research of Janice Kiecolt-Glaser: It informs self-care and the practice of medicine.Comprehensive psychoneuroendocrinology · 2024Review
- Is age more than a number? Accounting for adult development and aging in the study of psychoneuroimmunology, stress, and health.Comprehensive psychoneuroendocrinology · 2024Article
- Maternal caregiving stress and metabolic health: Sexual activity as a potential buffer.Psychoneuroendocrinology · 2024Article
- Leptin, Nesfatin-1, Orexin-A, and Total Ghrelin Levels in Drug-Naive Panic Disorder.Psychiatry investigation · 2024Article
- Fluctuations in depression and anxiety predict dysregulated leptin among obese breast cancer survivors.Journal of cancer survivorship : research and practice · 2021Article
- Measurement of the influences of social processes in appetite using ecological momentary assessment.Appetite · 2021Article
- Social modulation of ageing: mechanisms, ecology, evolution.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Review
- Threats to Belonging, Immune Function, and Eating Behavior: an Examination of Sex and Gender Differences.Current psychiatry reports · 2018Review
- Early Childhood Obesity Risk Factors: Socioeconomic Adversity, Family Dysfunction, Offspring Distress, and Junk Food Self-Medication.Current obesity reports · 2018Review
- A Role for Exercise in Attenuating Unhealthy Food Consumption in Response to Stress.Nutrients · 2018Review
- Influence of emotions evoked by life events on food choice.Eating and weight disorders : EWD · 2018Article
- Altered Feeding Behaviors and Adiposity Precede Observable Weight Gain in Young Rats Submitted to a Short-Term High-Fat Diet.Journal of nutrition and metabolism · 2018Article
- MELDNa score is associated with psychopathology and reduced quality of life in cirrhotic patients with a liver transplant perspective.Metabolic brain disease · 2017Article
- Neonatal overfeeding disrupts pituitary ghrelin signalling in female rats long-term; Implications for the stress response.PloS one · 2017Article
- Job Stress and Neuropeptide Response Contributing to Food Intake Regulation.Toxicological research · 2015Article
- Successive Generations in a Rat Model Respond Differently to a Constant Obesogenic Environment.PloS one · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveStressful events enhance risk for weight gain and adiposity. Ghrelin and leptin, two hormones that are implicated in appetite regulation, may link stressful events to weight gain; a number of rodent studies suggest that stressors increase ghrelin production. The present study investigated the links among daily stressors, ghrelin and leptin, and dietary intake in humans.
methodWomen (n=50) completed three study appointments that were scheduled at least 2 weeks apart. At each visit, women arrived fasting and ate a standardized breakfast and lunch. Blood samples were collected 45min after each meal. Women completed a self-report version of the Daily Inventory of Stressful Events (DISE) at each appointment. Two composites were created from the DISE data, reflecting the number of stressors that did and did not involve interpersonal tension.
resultsWomen who experienced more stressors involving interpersonal tension had higher ghrelin and lower leptin levels than those who experienced fewer interpersonal stressors. Furthermore, women who experienced more interpersonal stressors had a diet that was higher in calories, fat, carbohydrates, protein, sugar, sodium, and fiber, and marginally higher in cholesterol, vegetables (but not fruits), vitamin A, and vitamin C. Stressors that did not involve interpersonal tension were unrelated to ghrelin and leptin levels or any of the dietary components examined.
conclusionsThese data suggest that ghrelin and leptin may link daily interpersonal stressors to weight gain and obesity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.