ArticlePloS one2014
Metallothionein 2 (SaMT2) from Sedum alfredii Hance confers increased Cd tolerance and accumulation in yeast and tobacco.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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29 citing papers in PubMed, 103 citations in OpenAlex.
- Enhanced Phytoextraction Technologies for the Sustainable Remediation of Cadmium-Contaminated Soil Based on Hyperaccumulators-A Review.Plants (Basel, Switzerland) · 2025Review
- Systematic evaluation of plant metals/metalloids accumulation efficiency: a global synthesis of bioaccumulation and translocation factors.Frontiers in plant science · 2025Review
- Transcriptomic Analysis for Diurnal Temperature Differences Reveals Gene-Regulation-Network Response to Accumulation of Bioactive Ingredients of Protocorm-like Bodies inPlants (Basel, Switzerland) · 2024Article
- Genome-Wide Survey of theInternational journal of molecular sciences · 2023Article
- Exploring Transcriptional Regulation of Hyperaccumulation inInternational journal of molecular sciences · 2023Article
- Tobacco as an efficient metal accumulator.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2023Review
- Arbuscular mycorrhizal fungi improve selenium uptake by modulating root transcriptome of rice (Oryza sativa L.).Frontiers in plant science · 2023Article
- Exogenous silicon promotes cadmium (Cd) accumulation inFrontiers in plant science · 2023Article
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- Editing of a Novel Cd Uptake-Related GeneCells · 2022Article
- Transcriptome Analysis Reveals the Stress Tolerance to and Accumulation Mechanisms of Cadmium inPlants (Basel, Switzerland) · 2022Article
- Knowledge Mapping of the Phytoremediation of Cadmium-Contaminated Soil: A Bibliometric Analysis from 1994 to 2021.International journal of environmental research and public health · 2022Review
- Genome-Wide Characterization, Evolutionary Analysis ofPlants (Basel, Switzerland) · 2022Article
- Utilization of Legume-Nodule Bacterial Symbiosis in Phytoremediation of Heavy Metal-Contaminated Soils.Biology · 2022Review
- Genome-wide analysis of metallothionein gene family in maize to reveal its role in development and stress resistance to heavy metal.Biological research · 2022Article
- Increase in Phytoextraction Potential by Genome Editing and Transformation: A Review.Plants (Basel, Switzerland) · 2021Review
- Over-expression of chickpeaPhysiology and molecular biology of plants : an international journal of functional plant biology · 2021Article
- Recent advances in physiological and molecular mechanisms of heavy metal accumulation in plants.Environmental science and pollution research international · 2021Review
- Differential responses of thiol metabolism and genes involved in arsenic detoxification in tolerant and sensitive genotypes of bioenergy crop Ricinus communis.Protoplasma · 2021Article
- Inoculation With Indigenous Rhizosphere Microbes Enhances Aboveground Accumulation of Lead inFrontiers in microbiology · 2021Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Metallothioneins are cysteine-rich metal-binding proteins. In the present study, SaMT2, a type 2 metallothionein gene, was isolated from Cd/Zn co-hyperaccumulator Sedum alfredii Hance. SaMT2 encodes a putative peptide of 79 amino acid residues including two cysteine-rich domains. The transcript level of SaMT2 was higher in shoots than in roots of S. alfredii, and was significantly induced by Cd and Zn treatments. Yeast expression assay showed SaMT2 significantly enhanced Cd tolerance and accumulation in yeast. Ectopic expression of SaMT2 in tobacco enhanced Cd and Zn tolerance and accumulation in both shoots and roots of the transgenic plants. The transgenic plants had higher antioxidant enzyme activities and accumulated less H2O2 than wild-type plants under Cd and Zn treatment. Thus, SaMT2 could significantly enhance Cd and Zn tolerance and accumulation in transgenic tobacco plants by chelating metals and improving antioxidant system.
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