Evidence map›Paper›PMID 25032137›Full record

ArticleNephro-urology monthly2014

Ubiquinol effect on sperm parameters in subfertile men who have astheno-teratozoospermia with normal sperm concentration.

Basri Cakiroglu, Seyit Erkan Eyyupoglu, Ramazan Gozukucuk, Bekir Sami Uyanik

Open access · hybridAbstract read
In one paragraph

Article in Nephro-urology monthly, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Role of Coenzyme QAntioxidants (Basel, Switzerland) · 2021
    Review
  5. Coenzyme Q10 and Male Infertility: A Systematic Review.Antioxidants (Basel, Switzerland) · 2021
    Review
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Basri CakirogluDepartment of Urology, Hisar Intercontinental Hospital, Istanbul, Turkey.
Seyit Erkan EyyupogluDepartment of Urology, Sabuncuoglu Serefeddin Training and Research Hospital, Amasya, Turkey.
Ramazan GozukucukDepartment of Infectious Disease and Clinical Microbiology, Hisar Intercontinental Hospital, Istanbul, Turkey.
Bekir Sami UyanikDepartment of Clinical Biochemistry, Hisar Intercontinental Hospital, Istanbul, Turkey.
Amasya Üniversitesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundConsidering all the couples willing and trying to get pregnant, the incidence of infertility is 15% of which approximately half of the cases are due to the male factors.

objectivesThe aim of this study was the investigation of the effects of ubiquinol, reduced form of coenzyme Q10 (Co-Q10), an empiric treatment modality, on sperm parameters in idiopathic subfertility. PATIENTS AND

methodsIn this retrospective study, 62 patients who had received 100 mg ubiquinol twice a day for six months due to idiopathic infertility since January 2012 to January 2013 were included. Only infertile patients with astheno-teratozoospermia without any identified etiology and with a spermatozoa concentration of greater than 13 × 10(6)/mL were included.

resultsThe increase in mean values of concentration after the ubiquinol treatment was not statistically significant (P value = 0.065). However, the changes in morphology and motility (fast progressive [a] and a + slow progressive [b]) were statistically significant (P < 0.00).

conclusionsThe weakness of the literature with regard to coenzyme Q10 is about its effects in patients with severely diminished sperm densities and the physiologic steps of morphologic improvements.

Indexed as

IdiopathicInfertilityOligospermiaUbiquinol

Identifiers

PMID25032137
PMCPMC4090670
OpenAlexW2109807425

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.