ReviewEndocrinology and metabolism (Seoul, Korea)2014
Neurocognitive changes and their neural correlates in patients with type 2 diabetes mellitus.
Review in Endocrinology and metabolism (Seoul, Korea), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02416193 (Can Vitamin D3 Improve Cognitive Function in Individuals With Type 2 Diabetes?), which is not on this map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Can Vitamin D3 Improve Cognitive Function in Individuals With Type 2 Diabetes? (THINK-D)
Who cites it
22 citing papers in PubMed.
- Vitamin D Supplementation and Cognition in People with Type 2 Diabetes: A Randomized Control Trial.Journal of diabetes research · 2019Trial
- Ketogenic metabolic therapy: low-carbohydrate interventions as novel neuroprotective strategies for cognitive dysfunction in diabetes.Frontiers in aging neuroscience · 2026Review
- Diabetes mellitus and neurocognition: A report from the Childhood Cancer Survivor Study.Cancer · 2025Article
- Diabetes and associated cognitive disorders: Role of the Hypothalamic-Pituitary Adrenal axis.Metabolism open · 2022Review
- Type 2 Diabetes Independent of Glycemic Control is Associated With Cognitive Impairments: Findings From NHANES.Clinical nursing research · 2022Article
- Modifiable risk factors for neurocognitive and psychosocial problems after Hodgkin lymphoma.Blood · 2022Article
- Childhood Neurotoxicity and Brain Resilience to Adverse Events during Adulthood.Annals of neurology · 2021Article
- Promoting Successful Cognitive Aging: A Ten-Year Update.Journal of Alzheimer's disease : JAD · 2021Review
- Implementation of Imaging Methods in Evaluation of T2DM-Correlated Brain Alterations and Cognitive Dysfunction.Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : casopis Drustva za medicinsku informatiku BiH · 2020Review
- Benefits of combination low-dose pioglitazone plus fish oil on aged type 2 diabetes mice.Journal of food and drug analysis · 2018Article
- Diabetes, Depression, and Cognition: a Recursive Cycle of Cognitive Dysfunction and Glycemic Dysregulation.Current diabetes reports · 2018Review
- Association of ApoE Genetic Polymorphism and Type 2 Diabetes with Cognition in Non-Demented Aging Chinese Adults: A Community Based Cross-Sectional Study.Aging and disease · 2018Article
- Chronic Health Conditions and Neurocognitive Function in Aging Survivors of Childhood Cancer: A Report from the Childhood Cancer Survivor Study.Journal of the National Cancer Institute · 2018Article
- Insulin in the nervous system and the mind: Functions in metabolism, memory, and mood.Molecular metabolism · 2016Review
- 1,5-Anhydro-D-Glucitol Could Reflect Hypoglycemia Risk in Patients with Type 2 Diabetes Receiving Insulin Therapy.Endocrinology and metabolism (Seoul, Korea) · 2016Article
- Long-term Variability in Glycemic Control Is Associated With White Matter Hyperintensities in APOE4 Genotype Carriers With Type 2 Diabetes.Diabetes care · 2016Article
- Neurocognitive and Patient-Reported Outcomes in Adult Survivors of Childhood Osteosarcoma.JAMA oncology · 2016Article
- Toll-like receptor 2 and type 2 diabetes.Cellular & molecular biology letters · 2016Review
- Blood electrolyte disturbances during severe hypoglycemia in Korean patients with type 2 diabetes.The Korean journal of internal medicine · 2015Article
- Articles in 'endocrinology and metabolism' in 2014.Endocrinology and metabolism (Seoul, Korea) · 2015Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As the prevalence and life expectancy of type 2 diabetes mellitus (T2DM) continue to increase, the importance of effective detection and intervention for the complications of T2DM, especially neurocognitive complications including cognitive dysfunction and dementia, is receiving greater attention. T2DM is thought to influence cognitive function through an as yet unclear mechanism that involves multiple factors such as hyperglycemia, hypoglycemia, and vascular disease. Recent developments in neuroimaging methods have led to the identification of potential neural correlates of T2DM-related neurocognitive changes, which extend from structural to functional and metabolite alterations in the brain. The evidence indicates various changes in the T2DM brain, including global and regional atrophy, white matter hyperintensity, altered functional connectivity, and changes in neurometabolite levels. Continued neuroimaging research is expected to further elucidate the underpinnings of cognitive decline in T2DM and allow better diagnosis and treatment of the condition.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.