ArticleJournal of basic and clinical pharmacy2014
A clinical study on drug-related problems associated with intravenous drug administration.
Article in Journal of basic and clinical pharmacy, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
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Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Intravenous Medication Administration Errors in Hospitalised Patients: An Updated Systematic Review.Journal of evaluation in clinical practice · 2025Pooled it
- Incidence and prevalence of intravenous medication errors in the UK: a systematic review.European journal of hospital pharmacy : science and practice · 2020Pooled it
- Detection of intravenous drug physicochemical incompatibilities in clinical practice: e-Harvis compared to reference tools.European journal of clinical pharmacology · 2026Observational
- Rectal In Situ Thermosensitive Gel Loaded with Agomelatine-Silver Nanoparticles: Formulation and Characterization.Gels (Basel, Switzerland) · 2026Article
- Compatibility Investigation of a Steroid and Two Antibiotics with Heparin for the Prevention of Catheter Occlusion in Neonatal Intensive Care Units.Methods and protocols · 2025Article
- Systematic Review of Piperacillin-Tazobactam and Vancomycin Y-Site Compatibility: Consideration of Concentration and Solution Variability.Hospital pharmacy · 2023Review
- 25 years of maturation: A systematic review of RNAi in the clinic.Molecular therapy. Nucleic acids · 2023Review
- The Physical Compatibility of Glycopyrrolate and Rocuronium.Anesthesia progress · 2023Article
- Implementation of pharmacists' monitoring for intravenous drug compatibility.European journal of hospital pharmacy : science and practice · 2023Article
- Magnetically Actuated Shape Memory Polymers for On-Demand Drug Delivery.Materials (Basel, Switzerland) · 2022Article
- Strategies to prevent drug incompatibility during simultaneous multi-drug infusion in intensive care units: a literature review.European journal of clinical pharmacology · 2021Review
- Drug compatibility in neonatal intensive care units: gaps in knowledge and discordances.European journal of pediatrics · 2021Article
- Medication Safety in Intravenous Therapy: A Compatibility Study of Clonidine with Drugs Frequently Used in Intensive Care.Pharmaceutics · 2020Article
- Pharmacists in Critical Care.Innovations in pharmacy · 2019Article
- Optimal infusion rate in antimicrobial therapy explosion of evidence in the last five years.Infection and drug resistance · 2018Review
- Prevalence of intravenous medication administration errors: a cross-sectional study.Integrated pharmacy research & practice · 2017Article
- Improved usability of a multi-infusion setup using a centralized control interface: A task-based usability test.PloS one · 2017Article
- Methods to Reduce Medication Errors in a Clinical Trial of an Investigational Parenteral Medication.Contemporary clinical trials communications · 2016Article
- Drug-related problems in a sample of outpatients with chronic diseases: a cross-sectional study from Jordan.Therapeutics and clinical risk management · 2016Article
- Intravenous Drug Incompatibilities in the Intensive Care Unit of a Tertiary Care Hospital in India: Are they Preventable?Journal of research in pharmacy practiceArticle
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInfusion therapy through intravenous (IV) access is a therapeutic option used in the treatment of many hospitalized patients. IV therapy is complex, potentially dangerous and error prone. The objectives were to ascertain the drug-related problems (DRPs) involved in IV medication administration and further to develop strategies to reduce and prevent the occurrence of DRPs during IV administration. MATERIALS AND
methodsA prospective observational study was carried out for a period of 4 months. Patients receiving more than two medications through IV route were included and studied.
resultsOf 110 patients, 76 (69.09%) were male and the rest were female. Nearly, half of the patients (46.3%, n = 51) were reported with DRPs. Of the 80 DRPs (72.72%) documented, 61 problems (55.4%) were seen in patients given IV medications through peripheral line. Among the DRPs majority seen were incompatibilities (40.9%, n = 45), followed by complications developed (12.7%, n = 14), errors in rate of administration (10.9%), and dilution errors (8%). To study the association of DRPs among gender, statistical analysis was performed and significant association was seen between DRPs and gender (P = 0.03).
conclusionAmong the reported DRPs, simultaneous IV administration of two incompatible drugs was the main predicament faced.
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