Evidence map›Paper›PMID 25030960›Full record

SynthesisDer Unfallchirurg2014

[Management of complications in megaprostheses].

J Hardes, H Ahrens, G Gosheger, M Nottrott, R Dieckmann, M-P Henrichs, A Streitbürger

Abstract readEnglish AbstractMeta-AnalysisReview
PubMed Publisher
In one paragraph

Synthesis in Der Unfallchirurg, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Management of infection following reconstruction in bone tumors.Journal of clinical orthopaedics and trauma · 2015
    Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

J HardesKlinik für Allgemeine Orthopädie und Tumororthopädie, Universitätsklinikum Münster, Albert-Schweitzer-Campus 1, 48149, Münster, Deutschland, Jendrik.hardes@ukmuenster.de.
H Ahrens
G Gosheger
M Nottrott
R Dieckmann
M-P Henrichs
A Streitbürger

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMegaprostheses are frequently used after segmental resection of bone sarcomas, bone metastases, and in large osseous defects in revision arthroplasty.

objectivesThe incidence of the most common complications associated the use of megaprostheses are reported. The management of complications including therapeutic recommendations are described. MATERIALS AND

methodsThe current knowledge and our own experience of complication management with the use of megaprostheses are presented.

resultsProspective, randomized studies or meta-analyses on this topic are lacking. An analysis of the literature shows that beside the occurrence of a local recurrence, periprosthetic infection remains the most serious complication. Two-stage revision remains the gold standard, but a single-stage exchange of the prosthesis without removing the stems might be possible in selected cases. Infection is associated with a higher risk of secondary amputation. In contrast, mechanical failures (e.g., wear of the bushings in knee replacements and aseptic loosening of the stems) can be treated more easily. Dislocation of a proximal femur replacement can mostly be prevented by using bi- or tripolar cups.

conclusionsComplications with the use of megaprostheses can be successfully treated by revision surgery in most cases.

Indexed as

Bone NeoplasmsCausalityComorbidityHumansJoint ProsthesisOsteosarcomaPrevalenceProsthesis FailureProsthesis-Related InfectionsReoperationRisk FactorsTreatment Outcome

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.