ArticlePlanta2014
VuDREB2A, a novel DREB2-type transcription factor in the drought-tolerant legume cowpea, mediates DRE-dependent expression of stress-responsive genes and confers enhanced drought resistance in transgenic Arabidopsis.
Article in Planta, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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21 citing papers in PubMed.
- The SlDREBA4-SlASIL2 module mediates tomato thermotolerance by regulating the expression of SlHSP20/90.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Biogenic chlorapatite nanoparticles modulate stress-responsive genes and antioxidant defense to alleviate drought stress in Cowpea.BMC plant biology · 2026Article
- Unveiling the Genomic Architecture of Phenotypic Plasticity Using Multiple GWAS Approaches Under Contrasting Conditions of Water Availability: A Model for Barley.International journal of molecular sciences · 2026Article
- Unearthing the hidden organ: vital role of the root in drought tolerance of plants.Plant molecular biology · 2025Review
- Whole genome sequencing reveals transcriptional and translational elements potentially regulating biotic and abiotic stress responses in cowpea.Scientific reports · 2025Article
- A panomics-driven framework for the improvement of major food legume crops: advances, challenges, and future prospects.Horticulture research · 2025Article
- Combining the CowPEAsy Web Application With in Planta Agroinfiltration for Native Promoter Validation in Vigna unguiculata.Plant, cell & environment · 2025Article
- Transcription Factor VvDREB2A fromInternational journal of molecular sciences · 2023Article
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- Crop Wild Relatives: A Valuable Source of Tolerance to Various Abiotic Stresses.Plants (Basel, Switzerland) · 2023Review
- Growth responses and differential expression ofPhysiology and molecular biology of plants : an international journal of functional plant biology · 2021Article
- An Evolutionary Analysis of B-Box Transcription Factors in Strawberry Reveals the Role of FaBBx28c1 in the Regulation of Flowering Time.International journal of molecular sciences · 2021Article
- Identification and expression analysis of the DREB transcription factor family in pineapple (PeerJ · 2020Article
- Article
- Characterization of3 Biotech · 2018Article
- Characterization of CcSTOP1; a C2H2-type transcription factor regulates Al tolerance gene in pigeonpea.Planta · 2018Article
- Molecular characterisation of a DREB gene from Sophora moorcroftiana, an endemic species of plateau.Protoplasma · 2017Article
- Improvement and transcriptome analysis of root architecture by overexpression of Fraxinus pennsylvanica DREB2A transcription factor in Robinia pseudoacacia L. 'Idaho'.Plant biotechnology journal · 2016Article
- The AaDREB1 Transcription Factor from the Cold-Tolerant Plant Adonis amurensis Enhances Abiotic Stress Tolerance in Transgenic Plant.International journal of molecular sciences · 2016Article
- VrDREB2A, a DREB-binding transcription factor from Vigna radiata, increased drought and high-salt tolerance in transgenic Arabidopsis thaliana.Journal of plant research · 2016Article
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9 authors.
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Abstract
MAIN
conclusionVuDREB2A exists in cowpea as a canonical DREB2-type transcription factor, having the ability to bind dehydration-responsive elements in vitro and confer enhanced drought resistance in transgenic Arabidopsis. Cowpea (Vigna unguiculata L. Walp) is an important cultivated legume that can survive better in arid conditions than other crops. But the molecular mechanisms involved in the drought tolerance of this species remain elusive with very few reported candidate genes. The Dehydration-Responsive Element-Binding Protein2 (DREB2) group of transcription factors plays key roles in plant responses to drought. However, no DREB2 ortholog has been reported from cowpea so far. In this study, we isolated and characterized a gene from cowpea, namely VuDREB2A, encoding a protein of 377 amino acids exhibiting features of reported DREB2-type proteins. In cowpea, VuDREB2A transcript accumulation was highly induced by desiccation, heat and salt, but slightly by exogenous abscisic acid (ABA) treatment. We also isolated the VuDREB2A promoter and predicted stress-responsive cis-elements in it using Arabidopsis microarray data. The E. coli-expressed VuDREB2A protein showed binding to synthetic oligonucleotides with Dehydration-Responsive Elements (DREs) from Arabidopsis, in electrophoretic mobility shift assays. Heterologous expression of VuDREB2A in Arabidopsis significantly improved plant survival under drought. In addition, overexpression of a truncated version of VuDREB2A, after removal of a putative negative regulatory domain (between amino acids 132-182) led to a dwarf phenotype in the transgenic plants. Microarray and quantitative PCR analyses of VuDREB2A overexpressing Arabidopsis revealed up-regulation of stress-responsive genes having DRE overrepresented in their promoters. In summary, our results indicate that VuDREB2A conserves the basic functionality and mode of regulation of DREB2A in Arabidopsis and could be a potent candidate gene for the genetic improvement of drought resistance in cowpea.
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