Observational studyClinics (Sao Paulo, Brazil)2014
Nutritional parameters are associated with mortality in acute kidney injury.
Observational study in Clinics (Sao Paulo, Brazil), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Nutrition support for acute kidney injury 2020-consensus of the Taiwan AKI task force.Journal of the Chinese Medical Association : JCMA · 2022Pooled it
- Nitrogen balance and outcomes in critically ill patients: A systematic review and meta-analysis.Frontiers in nutrition · 2022Pooled it
- Protein-Energy Wasting Assessment and Clinical Outcomes in Patients with Acute Kidney Injury: A Systematic Review with Meta-Analysis.Nutrients · 2020Pooled it
- Low versus standard calorie and protein feeding and renal dysfunction in ventilated adults with shock: a NUTRIREA-3 post hoc analysis.Intensive care medicine · 2026Trial
- Prognostic significance of malnutrition risk in elderly patients with acute kidney injury in the intensive care unit.BMC nephrology · 2022Trial
- Lower energy intake associated with higher risk of cardiovascular mortality in chronic kidney disease patients on a low-protein diets.Nutrition journal · 2024Article
- Disruption in glutathione metabolism and altered energy production in the liver and kidney after ischemic acute kidney injury in mice.Scientific reports · 2024Article
- Clinical practice guidelines for nutritional assessment and monitoring of adult ICU patients in China.Journal of intensive medicine · 2024Article
- Early protein delivery in critically ill patients with acute kidney injury:Burns & trauma · 2024Article
- Association between nutritional status scores and the 30-day mortality in patients with acute kidney injury: an analysis of MIMIC-III database.BMC nephrology · 2023Article
- Article
- Proposal of a new equation for estimating resting energy expenditure of acute kidney injury patients on dialysis: a machine learning approach.Nutrition & metabolism · 2020Article
- Effect of prealbumin level on mortality in heatstroke patients.Experimental and therapeutic medicine · 2019Article
- Serum prealbumin and its changes over time are associated with mortality in acute kidney injury.Scientific reports · 2017Article
- Prognostic indicators of adverse renal outcome and death in acute kidney injury hospital survivors.Journal of renal injury prevention · 2016Article
- Comparison of two nutrition assessment tools in surgical elderly inpatients in Northern China.Nutrition journal · 2015Observational
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe objective of this study was to perform a nutritional assessment of acute kidney injury patients and to identify the relationship between nutritional markers and outcomes.
methodThis was a prospective and observational study. Patients who were hospitalized at the Hospital of Botucatu School of Medicine were evaluated between January 2009 and December 2011. We evaluated a total of 133 patients with a clinical diagnosis of acute kidney injury and a clinical presentation suggestive of acute tubular necrosis. We explored the associations between clinical, laboratory and nutritional markers and in-hospital mortality. Multivariable logistic regression was used to adjust for confounding and selection bias.
resultsNon-survivor patients were older (67 ± 14 vs. 59 ± 16 years) and exhibited a higher prevalence of sepsis (57.1 vs. 21.4%) and higher Acute Tubular Necrosis-Individual Severity Scores (0.60 ± 0.22 vs. 0.41 ± 0.21) than did survivor patients. Based on the multivariable analysis, laboratorial parameters such as blood urea nitrogen and C-reactive protein were associated with a higher risk of death (OR: 1.013, p=0.0052; OR: 1.050, p=0.01, respectively), and nutritional parameters such as low calorie intake, higher levels of edema, lower resistance based on bioelectrical impedance analysis and a more negative nitrogen balance were significantly associated with a higher risk of death (OR: 0.950, p=0.01; OR: 1.138, p=0.03; OR: 0.995, p=0.03; OR: 0.934, p=0.04, respectively).
conclusionsIn acute kidney injury patients, a nutritional assessment seems to identify nutritional markers that are associated with outcome. In this study, a low caloric intake, higher C-reactive protein levels, the presence of edema, a lower resistance measured during a bioelectrical impedance analysis and a lower nitrogen balance were significantly associated with risk of death in acute kidney injury patients.
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