ArticlePloS one2014
Sex specific incidence rates of type 2 diabetes and its risk factors over 9 years of follow-up: Tehran Lipid and Glucose Study.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 5 of them syntheses that pooled it.
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Who cites it
64 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- The effect of metformin therapy on serum thyrotropin and free thyroxine concentrations in patients with type 2 diabetes: a meta-analysis.Scientific reports · 2023Pooled it
- Association of wrist circumference with cardio-metabolic risk factors: a systematic review and meta-analysis.Eating and weight disorders : EWD · 2020Pooled it
- Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia.The Cochrane database of systematic reviews · 2018Pooled it
- Association of urinary cadmium with risk of diabetes: a meta-analysis.Environmental science and pollution research international · 2017Pooled it
- Pooled it
- The association between dietary intakes of nitrate with nitrite from animal and plant food sources and the incidence of metabolic syndrome: a prospective study.Nutrition journal · 2025Article
- The association between dietary intakes of nitrate with nitrite from animal and plant food sources and the incidence of pre-diabetes and type 2 diabetes: a prospective study.Nutrition & metabolism · 2025Article
- Incidence and predictors of type 2 diabetes mellitus during 17 years of follow-up in the Golestan Cohort Study.Scientific reports · 2025Article
- Associations between the Global Diet Quality Score and risk of type 2 diabetes: Tehran lipid and glucose study.PloS one · 2025Article
- Anthropometric Indices and Diabetes Disease: Based on the Rafsanjan Cohort Study.International journal of preventive medicine · 2025Article
- Linking extent of return to fasting state after oral glucose tolerance test to future risk of prediabetes and type 2 diabetes: Insights from the TLGS.Journal of diabetes investigation · 2024Article
- The association of ideal cardiovascular health metrics and incident hypertension among an urban population of Iran: a decade follow-up in Tehran Lipid and Glucose Study.Journal of human hypertension · 2024Article
- Estimated reductions in type 2 diabetes burden through nutrition policies in AZAR cohort population: A PRIME microsimulation study for primary health care.Health promotion perspectives · 2024Article
- Association between changes in thyroid hormones and incident type 2 diabetes using joint models of longitudinal and time-to-event data: more than a decade follow up in the Tehran thyroid study.Frontiers in endocrinology · 2024Article
- Resting heart rate and the risk of incident type 2 diabetes mellitus among non-diabetic and prediabetic Iranian adults: Tehran lipid and glucose study.BMC public health · 2023Article
- Impact of individual and environmental factors on dietary or lifestyle interventions to prevent type 2 diabetes development: a systematic review.Communications medicine · 2023Article
- External validation of the American prediction model for incident type 2 diabetes in the Iranian population.BMC medical research methodology · 2023Article
- Prevalence of anemia and its associated factors among patients with type 2 diabetes mellitus in a referral diabetic clinic in the north of Iran.BMC endocrine disorders · 2023Article
- Association of triglycerides to high-density lipoprotein cholesterol ratio to identify future prediabetes and type 2 diabetes mellitus: over one-decade follow-up in the Iranian population.Diabetology & metabolic syndrome · 2023Article
- Identification of the risk factors of type 2 diabetes and its prediction using machine learning techniques.Health systems (Basingstoke, England) · 2023Article
4 more citing papers are in PubMed but not listed here.
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Authors and funding
6 authors.
Funding
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Abstract
objectiveTo investigate the population-based incidence of type 2 diabetes and its potential risk factors in a sex-split cohort of Iranian population. MATERIALS AND
methodsA total of 8400 non-diabetic participants, aged ≥20 years (3620 men and 4780 women) entered the study. Crude and age standardized incidence rates per 1000 person-years were calculated for whole population and each sex separately. Cox proportional hazard models were used to evaluate hazard ratios (HR) and 95% confidence intervals for all potential risk factors in both uni-variable and multivariable models.
resultsDuring a median follow-up of 9.5 years, 736 new cases of diabetes were identified, including 433 women and 303 men. The annual crude and age-standardized incidence rates (95% CI) of diabetes in the total population were 10.6 (9.92-11.4) and 9.94 (7.39-13.6) per 1000 person-years of follow-up and the corresponding sex specific rates were 10.2 (9.13-11.4) and 9.36 (5.84-14.92) in men and 11.0 (9.99-12.0) and 10.1 (7.24-13.9) in women, respectively. In the multivariable model, the risk for incident diabetes was significantly associated with fasting and 2 hour post challenge plasma glucose as well as family history of diabetes in both men and women. However, among women, only the contribution of wrist circumference to incident diabetes achieved statistical significance [HR: 1.16 (1.03-1.31)] with waist/height ratio being marginally significant [HR: 1.02 (0.99-1.04)]; while among men, only body mass index was a significant predictor [HR: 1.12 (1.02-1.22)]. Additionally, low education level conferred a higher risk for incident diabetes only among men [HR: 1.80 (1.23-2.36); P for interaction with sex = 0.003].
conclusionOverall, sex did not significantly modify the impact of risk factors associated with diabetes among Iranian adults; however, among modifiable risk factors, the independent role of lower education and general adiposity in men and central adiposity in women might require different preventive strategies.
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