ArticleThe Journal of infectious diseases2015
Disparity in the persistence of high-risk human papillomavirus genotypes between African American and European American women of college age.
Article in The Journal of infectious diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.
- Association Between Vaginal Microbiota and Cervical Dysplasia Due to Persistent Human Papillomavirus Infection: A Systematic Review of Evidence from Shotgun Metagenomic Sequencing Studies.International journal of molecular sciences · 2025Pooled it
- Racial/ethnic differences in HPV 16/18 genotypes and integration status among women with a history of cytological abnormalities.Gynecologic oncology · 2018Trial
- Disparities and trends of the incidence and mortality of female-specific cancers in the United States.PloS one · 2025Article
- Temporal trends of cervical cancer demographics: a CDC WONDER database study.Frontiers in oncology · 2025Article
- Barriers to and opportunities for advancing racial equity in cervical cancer screening in the United States.BMC women's health · 2024Article
- Risk Factors for Cervical Cancer in Ghana.Cancer reports (Hoboken, N.J.) · 2024Article
- Does the Vaginal Microbiome Operate Differently by Race to Influence Risk of Precervical Cancer?Journal of women's health (2002) · 2023Article
- Disparities in awareness of the HPV vaccine and HPV-associated cancers among racial/ethnic minority populations: 2018 HINTS.Ethnicity & health · 2023Article
- Factors associated with HPV vaccine acceptability and hesitancy among Black mothers with young daughters in the United States.Frontiers in public health · 2023Article
- Perceived Stress and Molecular Bacterial Vaginosis in the National Institutes of Health Longitudinal Study of Vaginal Flora.American journal of epidemiology · 2021Article
- The impact of socioeconomic status on HPV infection among young Brazilians in a nationwide multicenter study.Preventive medicine reports · 2021Article
- Evaluation of PCR-Reverse Dot Blot Human Papillomavirus Genotyping Test in Predicting Residual/Recurrent CIN 2+ in Posttreatment Patients in China.Cancer management and research · 2020Article
- Regional variations in human papillomavirus prevalence across time in NHANES (2003-2014).Vaccine · 2019Article
- Disparities in HPV vaccination rates and HPV prevalence in the United States: a review of the literature.Human vaccines & immunotherapeutics · 2019Review
- High Rates of High-Grade Cervical Dysplasia in High-Risk Young Women With Low-Grade Cervical Cytology.Journal of lower genital tract disease · 2018Article
- Global Inequities in Precision Medicine and Molecular Cancer Research.Frontiers in oncology · 2018Review
- Barriers to HPV Vaccination Among Unvaccinated, Haitian American College Women.Health equity · 2018Article
- Racial Disparity in Gastrointestinal Cancer Risk.Gastroenterology · 2017Review
- High-risk human papillomavirus seroprevalence in men and women of six different ethnicities in Amsterdam, the Netherlands: The HELIUS study.Papillomavirus research (Amsterdam, Netherlands) · 2017Article
- Disparity in rates of HPV infection and cervical cancer in underserved US populations.Frontiers in bioscience (Scholar edition) · 2017Review
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
backgroundCervical cancer incidence and mortality rates are higher in African Americans than in European Americans (white, non-Hispanic of European ancestry). The reasons for this disparity are not known.
methodsWe recruited a population-based longitudinal cohort of 326 European American and 113 African American female college freshmen in Columbia, South Carolina, to compare clearance of high-risk human papillomavirus (HR-HPV) infection between ethnicities. HPV testing and typing from samples obtained for Papanicolaou testing occurred every 6 months.
resultsAfrican American participants had an increased risk of testing positive for HR-HPV, compared with European American participants, but the frequency of incident HPV infection was the same in African American and European American women. Thus, exposure to HPV could not explain the higher rate of HPV positivity among African American women. The time required for 50% of participants to clear HR-HPV infection was 601 days for African American women (n = 63) and 316 days for European American women (n = 178; odds ratio [OR], 1.61; 95% confidence interval [CI], 1.08-2.53). African American women were more likely than European American women to have an abnormal result of a Papanicolaou test (OR, 1.58; 95% CI, 1.05-2.39).
conclusionsWe propose that the longer time to clearance of HR-HPV among African American women leads to increased rates of abnormal results of Papanicolaou tests and contributes to the increased rates of cervical cancer observed in African American women.
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