Evidence map›Paper›PMID 25028600›Full record

ArticleGut pathogens2014

Genome sequencing, annotation and comparative genomic analysis of Shigella dysenteriae strain SD1D.

Gurwinder Kaur, Sathyaseelan Sathyabama, Amit Arora, Sheenam Verma, Nida Mubin, Javed N Agrewala, Shanmugam Mayilraj

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Gut pathogens, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Structural and Physiological Exploration ofFrontiers in microbiology · 2018
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Gurwinder Kaur *Microbial Type Culture Collection and Gene bank, CSIR-Institute of Microbial Technology, Sector 39A, Chandigarh 160036, India.
Sathyaseelan Sathyabama *Immunology Laboratory, CSIR-Institute of Microbial Technology, Sector 39A, Chandigarh 160036, India.
Amit AroraMicrobial Type Culture Collection and Gene bank, CSIR-Institute of Microbial Technology, Sector 39A, Chandigarh 160036, India.
Sheenam VermaImmunology Laboratory, CSIR-Institute of Microbial Technology, Sector 39A, Chandigarh 160036, India.
Nida MubinImmunology Laboratory, CSIR-Institute of Microbial Technology, Sector 39A, Chandigarh 160036, India.
Javed N AgrewalaImmunology Laboratory, CSIR-Institute of Microbial Technology, Sector 39A, Chandigarh 160036, India.
Shanmugam MayilrajMicrobial Type Culture Collection and Gene bank, CSIR-Institute of Microbial Technology, Sector 39A, Chandigarh 160036, India.
Institute of Microbial Technology · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundShigellosis is an acute form of gastroenteritis caused by the bacteria belonging to the genus Shigella. It is the most common cause of morbidity and mortality in children. Shigella belongs to the family Enterobactericeae, which is a Gram-negative and rod shaped bacterium. In the present study, we report the draft genome of Shigella dysenteriae strain SD1D, which was isolated from the stool sample of a healthy individual.

resultsBased on 16S rRNA gene sequence and phylogenetic analysis, the strain SD1D was identified as Shigella dysenteriae. The draft genome of SD1D consisted of 45, 93, 159 bp with a G + C content of 50.7%, 4, 960 predicted CDSs, 75 tRNAs and 2 rRNAs. The final assembly contained 146 contigs of total length 45, 93, 159 bp with N50 contig length of 77, 053 bp; the largest contig assembled measured 3, 85, 550 bp.

conclusionsWe have for the first time performed the whole genome sequencing of Shigella dysenteriae strain SD1D. The comparative genomic analysis revealed several genes responsible for the pathogenesis, virulence, defense, resistance to antibiotics and toxic compounds, multidrug resistance efflux pumps and other genomic features of the bacterium.

Indexed as

EzTaxonG + C contentRASTShigella dysenteriaeShigellosis

Identifiers

PMID25028600
PMCPMC4099087
OpenAlexW2095658308

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.