ArticleJournal of pain research2014
The importance of catastrophizing for successful pharmacological treatment of peripheral neuropathic pain.
Article in Journal of pain research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Identifying predictors of neuropathic pain medication prescribing, adherence, and discontinuation: a systematic review and meta-analysis.British journal of anaesthesia · 2026Pooled it
- A longitudinal assessment of posttraumatic stress symptoms and pain catastrophizing after injury.Rehabilitation psychology · 2023Trial
- Pain Catastrophizing: Mechanisms and Clinical Implications.Journal of pain research · 2026Review
- Response to High-Dose Topical Capsaicin in Neuropathic Pain: Absence of Deep Pain as a Predictor of Analgesic Effect.European journal of pain (London, England) · 2026Article
- Review
- Interdisciplinary pain program participants with high catastrophizing scores improve function utilizing enriched therapeutic encounters and integrative health techniques: a retrospective study.Frontiers in psychology · 2024Article
- Pain-Related Coping Behavior in ALS: The Interplay between Maladaptive Coping, the Patient's Affective State and Pain.Journal of clinical medicine · 2022Article
- Revealing the Role of Social Support on Cognitive Deficits in Fibromyalgia Syndrome.Behavioural neurology · 2022Article
- Mindfulness-based stress reduction alters brain activity for breast cancer survivors with chronic neuropathic pain: preliminary evidence from resting-state fMRI.Journal of cancer survivorship : research and practice · 2021Article
- Pain catastrophizing mediates the negative influence of pain and trait-anxiety on health-related quality of life in fibromyalgia.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2020Article
- Negative health consequences of pain catastrophizing among retired National Football League athletes.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2020Article
- Evaluating psychosocial contributions to chronic pain outcomes.Progress in neuro-psychopharmacology & biological psychiatry · 2018Review
- Effect of gastroretentive gabapentin (Gralise) on postmastectomy pain syndrome: a proof-of-principle open-label study.Pain reports · 2017Article
- Pain and Psychology-A Reciprocal Relationship.Ochsner journal · 2017Review
- Psychological Considerations in the Assessment and Treatment of Pain in Neurorehabilitation and Psychological Factors Predictive of Therapeutic Response: Evidence and Recommendations from the Italian Consensus Conference on Pain in Neurorehabilitation.Frontiers in psychology · 2016Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveCatastrophizing may be a negative predictor of pain-related outcomes. We evaluated the impact of catastrophizing upon success of first-line pharmacotherapy in the management of neuropathic pain (NeP) due to peripheral polyneuropathy.
methodsPatients with confirmed NeP with NeP Visual Analog Scale (VAS) pain severity score ≥4 (0-10 scale) completed the Coping Strategies Questionnaire (CSQ) catastrophizing subscale at baseline. Pharmacological therapy consisting of first-line agents gabapentin, pregabalin, or a tricyclic antidepressant was initiated. Other measures examined included the Karnofsky Performance Scale, Beck Depression Inventory, EuroQol Quality of Life Health Questionnaire, and Modified Brief Pain Inventory. At 3 and 6 months, questionnaires were repeated and adverse effect reporting was completed. Outcome measures assessed were pharmacotherapy success (≥30% relief of NeP) and tolerability over 6 months of follow-up. Bivariate relationships using Pearson product-moment correlations were examined for baseline CSQ catastrophizing subscale score and the change in the NeP VAS scores and medication discontinuation.
resultsSixty-six patients were screened, 62 subjects participated, and 58 subjects (94%) completed the final follow-up visit. Greater catastrophizing was associated with poor pain relief response and greater likelihood of discontinuation of pharmacotherapy, reports of greater disability, and impaired quality of life. Duration of pain was negatively associated with likelihood of pharmacotherapy success.
conclusionCatastrophizing exerts maladaptive effects on outcomes with pharmacotherapy in NeP patients. Detection of catastrophizing during clinical visits when pharmacological therapy is being considered can be a predictive factor for patient outcomes.
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Registered trials
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