ArticleSurgical endoscopy2015
Technical description and feasibility of laparoscopic adrenal contouring using fluorescence imaging.
Article in Surgical endoscopy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 28 citations in OpenAlex.
- Application of indocyanine green fluorescence imaging in cortical-sparing adrenalectomy: a preliminary study with image quantification techniques.Surgical endoscopy · 2026Article
- Impact of indocyanine green on decision making for performing laparoscopic cortical sparing adrenalectomy.Updates in surgery · 2024Article
- Imaging guided adrenalectomy with Indocyanine green fluorescence in a dog with a pheochromocytoma.Journal of veterinary science · 2024Article
- Fluorescence imaging to visualize the recurrent laryngeal nerve during thyroidectomy procedures: analysis of 65 cases and 81 nerves.Surgical endoscopy · 2024Article
- Characterization of indocyanine green fluorescence imaging patterns of pheochromocytomas.Surgical endoscopy · 2023Article
- Challenges and controversies in adrenal surgery: A practical approach.Current problems in surgery · 2023Article
- Adrenal Near-Infrared Autofluorescence.Journal of the Endocrine Society · 2022Article
- A visual quantification of tissue distinction in robotic transabdominal lateral adrenalectomy: comparison of indocyanine green and conventional views.Surgical endoscopy · 2022Article
- Indocyanine green fluorescence imaging for robotic adrenalectomy.Gland surgery · 2020Review
- Indocyanine green fluorescence imaging during partial adrenalectomy.Surgical endoscopy · 2020Article
- Fluorescence-enabled assessment of adrenal gland localization and perfusion in posterior retroperitoneoscopic adrenal surgery in a preclinical model.Surgical endoscopy · 2020Article
- Role of indo-cyanine green (ICG) fluorescence in laparoscopic adrenalectomy: a retrospective review of 55 Cases.Surgical endoscopy · 2018Article
- Accuracy of Near Infrared-Guided Surgery in Morbidly Obese Subjects Undergoing Laparoscopic Cholecystectomy.Obesity surgery · 2016Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIdentification of adrenal glands from the surrounding structures during laparoscopic surgery can be challenging especially in obese individuals. This can increase the chances for hemorrhage and conversion to open surgery. We present the first report of fluorescent infrared visualization of the adrenal glands in a large animal model.
methodsFive adult Yorkshire pigs were utilized for the study, in compliance with the animal study regulations. After an intravenous bolus administration of 3 mL of indocyanine green (ICG), visualization was performed with a xenon/infrared light source and a laparoscope with a charge-coupled filter device. Activation of the device was done with a foot pedal. Images were analyzed using histogram software and the difference of enhancement was statistically analyzed using unpaired two-tailed t test.
resultsThe right adrenal glands were visualized in all five animals immediately after administering ICG. Fluorescence facilitated demarcation of adrenal gland tissue from surrounding adipose tissue. Peritoneum and fat was visualized in black color. Adrenal enhancement lasted for 4 h in all cases. The mean value for adrenal fluorescence using histogram count was 71.75 pixels, and for adrenal xenon was 168.87 pixels (p = 0.0002; 95 % CI -130.93 to -0.63). The mean value for fat fluorescence using histogram count was 5.54 pixels and fat xenon was 187.15 pixels (p = 0.0001; 95 % CI -199.39 to -163.82). Although there was no significant difference between adrenal and fat enhancement with xenon light (p = 0.24; 95 % CI -15.53 to 52.09), the difference became significant between adrenal and fat fluorescence (p = 0.0001; 95 % CI 48.51-83.9).
conclusionFluorescence imaging appears to be a feasible and easy method to differentiate adrenal glands from the surrounding tissue in a large animal model. Further studies are necessary to investigate the real application of this method during laparoscopic adrenalectomy in humans.
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