Evidence map›Paper›PMID 25027361›Full record

ArticleThe Journal of pediatrics2014

Cat and dog exposure and respiratory morbidities in cystic fibrosis.

Christopher B Morrow, Karen S Raraigh, Deanna M Green, Scott M Blackman, Garry R Cutting, Joseph M Collaco

Abstract readMulticenter StudyTwin Study
In one paragraph

Article in The Journal of pediatrics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Christopher B MorrowEudowood Division of Pediatric Respiratory Sciences, Baltimore, MD.
Karen S RaraighInstitute of Genetic Medicine, Baltimore, MD.
Deanna M GreenEudowood Division of Pediatric Respiratory Sciences, Baltimore, MD.
Scott M BlackmanDivision of Pediatric Endocrinology, The Johns Hopkins Medical Institutions, Baltimore, MD.
Garry R CuttingInstitute of Genetic Medicine, Baltimore, MD.
Joseph M CollacoEudowood Division of Pediatric Respiratory Sciences, Baltimore, MD. Electronic address: mcollac1@jhmi.edu.

Funding

Genetic Modifiers of Cystic Fibrosis: Sibling StudyR01HL068927 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI CUTTING, GARRY R · 2001 to 2011
$8.9M
NHLBI NIH HHS 5R01HL068927-09NHLBI NIH HHS R01 HL068927
6 · The paper itself

Abstract

objectiveTo understand the triggers that may impact respiratory health in cystic fibrosis (CF), including the effects of pets, because environmental factors contribute to one-half of the variation in lung function in patients with CF. STUDY

designA total of 703 subjects with CF were recruited through the US CF Twin-Sibling Study. Questionnaires were used to determine the presence/absence of cats and dogs in households with a child with CF. Questionnaires, chart review, and US CF Foundation Patient Registry data were used to track respiratory and infection outcomes.

resultsWithin the sample, 47% of subjects reported owning a dog, and 28% reported owning a cat. After adjustment for demographic factors, dog ownership was not associated with any adverse clinical outcomes, and cat ownership was associated an increased risk in developing nasal polyps (aOR 1.66; P = .024) compared with noncat owners. Subjects who owned both cats and dogs were twice as likely to report wheezing compared with other subjects (aOR: 2.01; P = .009). There were no differences in prevalence and age of acquisition for the common CF respiratory pathogens Pseudomonas aeruginosa and methicillin-resistant Staphylococcus aureus between cat/dog owners and noncat/dog owners.

conclusionsCat ownership was associated with a greater frequency of developing nasal polyps and combined cat-dog ownership was associated with a greater rate of wheezing. Prospective studies are needed to confirm these associations and the potential psychosocial benefits of cat and/or dog ownership.

Indexed as

CatsDogsPetsAdolescentAdultAge FactorsAnimalsChildChild, PreschoolCystic FibrosisFemaleHumansInfantMaleMethicillin-Resistant Staphylococcus aureusMiddle Aged

Identifiers

PMID25027361
PMCPMC4177281

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.