ReviewMedical science monitor : international medical journal of experimental and clinical research2014
Epigenetic modification of DRG neuronal gene expression subsequent to nerve injury: etiological contribution to complex regional pain syndromes (Part II).
Review in Medical science monitor : international medical journal of experimental and clinical research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Review
- Biochemical analysis of miR-217 and miR-532 in patients with fibromyalgia.European journal of medical research · 2025Article
- FUS Contributes to Nerve Injury-Induced Nociceptive Hypersensitivity by Activating NF-κB Pathway in Primary Sensory Neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Review
- Profile of dorsal root ganglion neurons: study of oxytocin expression.Molecular brain · 2022Article
- Influence of gap junctions upon CaBiophysics and physicobiology · 2022Article
- Fibromyalgia: Pathogenesis, Mechanisms, Diagnosis and Treatment Options Update.International journal of molecular sciences · 2021Review
- DNA methylation profiles are associated with complex regional pain syndrome after traumatic injury.Pain · 2019Article
- Dysregulated mitochondrial and chloroplast bioenergetics from a translational medical perspective (Review).International journal of molecular medicine · 2016Review
- MicroRNA-30b regulates expression of the sodium channel Nav1.7 in nerve injury-induced neuropathic pain in the rat.Molecular pain · 2016Article
- Mitochondria, Chloroplasts in Animal and Plant Cells: Significance of Conformational Matching.Medical science monitor : international medical journal of experimental and clinical research · 2015Review
- Mitochondria and chloroplasts shared in animal and plant tissues: significance of communication.Medical science monitor : international medical journal of experimental and clinical research · 2015Review
- Hypoxia defined as a common culprit/initiation factor in mitochondrial-mediated proinflammatory processes.Medical science monitor : international medical journal of experimental and clinical research · 2015Review
- Epigenetic regulation of chronic pain.Epigenomics · 2015Review
- Algodystrophy (CRPS) in minor orthopedic surgery.Clinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal DiseasesReview
- Fibromyalgia: Genetics and epigenetics insights may provide the basis for the development of diagnostic biomarkers.Molecular painReview
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cumulating evidence indicated that nerve injury-associated cellular and molecular changes play an essential role in contributing to the development of pathological pain, and more recent findings implicated the critical role of epigenetic mechanisms in pain-related sensitization in the DRG subsequent to nerve injury. In this part of the dyad review (Part II), we reviewed and paid special attention on the etiological contribution of DGR gene expression modulated by epigenetic mechanisms of CRPS. As essential effectors to different molecular activation, we first discussed the activation of various signaling pathways that subsequently from nerve injury, and in further illustrated the fundamental and functional underpinnings of nerve injury-induced pain, in which we argued for the potential epigenetic mechanisms in response to sensitizing stimuli or injury. Therefore, understanding the specific mediating factors that influence individual epigenetic differences contributing to pain sensitivity and responsiveness to analgesics possesses crucial clinical implications.
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