ArticleACS applied materials & interfaces2014
Size-tunable and monodisperse Tm³⁺/Gd³⁺-doped hexagonal NaYbF₄ nanoparticles with engineered efficient near infrared-to-near infrared upconversion for in vivo imaging.
Article in ACS applied materials & interfaces, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 153 citations in OpenAlex.
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- Machine-Learning Single-Stranded DNA Nanoparticles for Bacterial Analysis.ACS applied nano materials · 2020Article
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- Contemporary Synthesis of Ultrasmall (sub-10 nm) Upconverting Nanomaterials.ChemistryOpen · 2020Review
- Divalent europium-doped near-infrared-emitting phosphor for light-emitting diodes.Nature communications · 2019Article
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- Revisiting the Enhanced Red Upconversion Emission from a Single β-NaYFNanoscale research letters · 2019Article
- Single upconversion nanoparticle imaging at sub-10 W cmNature photonics · 2018Article
- Revealing theRSC advances · 2018Article
- Rapid Synthesis of Sub-10 nm Hexagonal NaYFChemistryOpen · 2018Article
- Polymeric nanocapsules with up-converting nanocrystals cargo make ideal fluorescent bioprobes.Scientific reports · 2016Article
- Controlling the Two-Photon-Induced Photon Cascade Emission in a Gd(3+)/Tb(3+)-Codoped Glass for Multicolor Display.Scientific reports · 2016Article
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Authors and funding
8 authors at 3 institutions in 4 countries.
Funding
Abstract
Hexagonal NaYbF4:Tm(3+) upconversion nanoparticles hold promise for use in high contrast near-infrared-to-near-infrared (NIR-to-NIR) in vitro and in vivo bioimaging. However, significant hurdles remain in their preparation and control of their morphology and size, as well as in enhancement of their upconversion efficiency. Here, we describe a systematic approach to produce highly controlled hexagonal NaYbF4:Tm(3+) nanoparticles with superior upconversion. We found that doping appropriate concentrations of trivalent gadolinium (Gd(3+)) can convert NaYbF4:Tm(3+) 0.5% nanoparticles with cubic phase and irregular shape into highly monodisperse NaYbF4:Tm(3+) 0.5% nanoplates or nanospheres in a pure hexagonal-phase and of tunable size. The intensity and the lifetime of the upconverted NIR luminescence at 800 nm exhibit a direct dependence on the size distribution of the resulting nanoparticles, being ascribed to the varied surface-to-volume ratios determined by the different nanoparticle size. Epitaxial growth of a thin NaYF4 shell layer of ∼2 nm on the ∼22 nm core of hexagonal NaYbF4:Gd(3+) 30%/Tm(3+) 0.5% nanoparticles resulted in a dramatic 350 fold NIR upconversion efficiency enhancement, because of effective suppression of surface-related quenching mechanisms. In vivo NIR-to-NIR upconversion imaging was demonstrated using a dispersion of phospholipid-polyethylene glycol (DSPE-PEG)-coated core/shell nanoparticles in phosphate buffered saline.
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