Evidence map›Paper›PMID 25026465›Full record

ReviewSeminars in cell & developmental biology2014

Modelling from the experimental developmental biologists viewpoint.

Andrew D Economou, Jeremy B A Green

Abstract readReview
In one paragraph

Review in Seminars in cell & developmental biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Time and space in segmentation.Interface focus · 2021
    Article
  3. Bespoke Turing Systems.Bulletin of mathematical biology · 2021
    Article
  4. Article
  5. Article
  6. Forging patterns and making waves from biology to geology: a commentary on Turing (1952) 'The chemical basis of morphogenesis'.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Andrew D EconomouDepartment of Craniofacial Development & Stem Cell Biology, Guy's Tower, Floor 27, London SE1 9RT, United Kingdom.
Jeremy B A GreenDepartment of Craniofacial Development & Stem Cell Biology, Guy's Tower, Floor 27, London SE1 9RT, United Kingdom. Electronic address: jeremy.green@kcl.ac.uk.

Funding

Biotechnology and Biological Sciences Research Council BB/J009105/1Biotechnology and Biological Sciences Research Council BB/L002965/1Medical Research Council G0801154
6 · The paper itself

Abstract

In this review we consider Reaction-Diffusion as the archetype of a model in developmental biology. We consider its history in relation to experimental work since it was first proposed in 1952 by Turing and revived in the 1970s by Meinhardt. We then discuss the most recent examples of experiments that address this model, including the challenges that remain in capturing the physico-chemical manifestation of the model mechanism in a real developmental system. Finally we discuss the model's current status and use in the experimental community.

Indexed as

Models, BiologicalAnimalsBody PatterningComputer SimulationDevelopmental BiologyDiffusionGene Expression Regulation, DevelopmentalHumansModels, ChemicalMorphogenesisChemical morphogenesisLALIMorphogensReaction–DiffusionTuring systems

Identifiers

PMID25026465
PMCPMC4196921

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.