Evidence map›Paper›PMID 25025601›Full record

Trial reportJournal of pediatric gastroenterology and nutrition2014

Iyengar yoga for adolescents and young adults with irritable bowel syndrome.

Subhadra Evans, Kirsten C Lung, Laura C Seidman, Beth Sternlieb, Lonnie K Zeltzer, Jennie C I Tsao

Registry-linked trialOpen access · greenAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Journal of pediatric gastroenterology and nutrition, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01107977 (Iyengar Yoga for Young People With Irritable Bowel Syndrome), which is not on this map. Cited by 34 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 9 pooled it
9.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01107977 nacompletednot on this map

Iyengar Yoga for Young People With Irritable Bowel Syndrome

TypeinterventionalSponsorUniversity of California, Los AngelesRan2010 to 2013Enrolled58ConditionsIrritable Bowel SyndromeArmsIyengar yoga
3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 9 syntheses or guidelines pooled it, 147 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Guideline
  4. Guideline
  5. Physical activity for treatment of irritable bowel syndrome.The Cochrane database of systematic reviews · 2022
    Pooled it
  6. Pooled it
  7. The effects of school-based interventions on physiological stress in adolescents: A meta-analysis.Stress and health : journal of the International Society for the Investigation of Stress · 2022
    Pooled it
  8. Pooled it
  9. Psychosocial interventions for recurrent abdominal pain in childhood.The Cochrane database of systematic reviews · 2017
    Pooled it
  10. Trial
  11. Trial
  12. Article
  13. Yoga in Pediatric Gastroenterology.Current gastroenterology reports · 2024
    Review
  14. Review
  15. Psychological/behavioral interventions for emerging adults with chronic pain.Frontiers in pain research (Lausanne, Switzerland) · 2024
    Review
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Subhadra EvansPediatric Pain Program, University of California, Los Angeles.
Kirsten C Lung
Laura C Seidman
Beth Sternlieb
Lonnie K Zeltzer
Jennie C I Tsao
University of California, Los Angeles · US

Funding

UCLA Clinical and Translational Science InstituteUL1TR000124 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DUBINETT, STEVEN M. · 2012 to 2015
$57.0M
Iyengar yoga for adolescents and young adults with irritable bowel syndromeK01AT005093 · NCCIH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI EVANS, SUBHADRA · 2010 to 2014
$690k
NCATS NIH HHS UL1 TR000124NCATS NIH HHS UL1TR000124NCCIH NIH HHS K01 AT005093NCCIH NIH HHS K01AT005093
6 · The paper itself

Abstract

objectivesIrritable bowel syndrome (IBS) is a chronic, disabling condition that greatly compromises patient functioning. The aim of this study was to assess the impact of a 6-week twice per week Iyengar yoga (IY) program on IBS symptoms in adolescents and young adults (YA) with IBS compared with a usual-care waitlist control group.

methodsAssessments of symptoms, global improvement, pain, health-related quality of life, psychological distress, functional disability, fatigue, and sleep were collected pre- and posttreatment. Weekly ratings of pain, IBS symptoms, and global improvement were also recorded until 2-month follow-up. A total of 51 participants completed the intervention (yoga = 29; usual-care waitlist = 22).

resultsBaseline attrition was 24%. On average, the yoga group attended 75% of classes. Analyses were divided by age group. Relative to controls, adolescents (14-17 years) assigned to yoga reported significantly improved physical functioning, whereas YA (18-26 years) assigned to yoga reported significantly improved IBS symptoms, global improvement, disability, psychological distress, sleep quality, and fatigue. Although abdominal pain intensity was statistically unchanged, 44% of adolescents and 46% of YA reported a minimally clinically significant reduction in pain following yoga, and one-third of YA reported clinically significant levels of global symptom improvement. Analysis of the uncontrolled effects and maintenance of treatment effects for adolescents revealed global improvement immediately post-yoga that was not maintained at follow-up. For YA, global improvement, worst pain, constipation, and nausea were significantly improved postyoga, but only global improvement, worst pain, and nausea maintained at the 2-month follow-up.

conclusionsThe findings suggest that a brief IY intervention is a feasible and safe adjunctive treatment for young people with IBS, leading to benefits in a number of IBS-specific and general functioning domains for YA. The age-specific results suggest that yoga interventions may be most fruitful when developmentally tailored.

Indexed as

Severity of Illness IndexYogaAbdominal PainActivities of Daily LivingAdolescentAdultAge FactorsFemaleHumansIrritable Bowel SyndromeMaleNauseaPatient DropoutsTreatment OutcomeYoung Adult

Identifiers

PMID25025601
PMCPMC4146428
OpenAlexW1965248036

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.