Evidence map›Paper›PMID 25025449›Full record

ReviewThe American journal of surgical pathology2014

Cytotoxic T-cell and NK-cell lymphomas: current questions and controversies.

Steven H Swerdlow, Elaine S Jaffe, Pierre Brousset, John K C Chan, Laurence de Leval, Philippe Gaulard, Nancy Lee Harris, Stefano Pileri, Lawrence M Weiss, International Lymphoma Study Group

Abstract readReview
In one paragraph

Review in The American journal of surgical pathology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 94 citations in OpenAlex.

  1. The Significance of the Microenvironment in T/Nk-Cell Neoplasms.International journal of molecular sciences · 2025
    Review
  2. Gastric T-cell lymphoma in a European wolf (Canis lupus lupus).The Journal of veterinary medical science · 2025
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  7. TCR Pathway Mutations in Mature T Cell Lymphomas.Journal of immunology (Baltimore, Md. : 1950) · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 4 countries.

Steven H Swerdlow*Department of Pathology, Division of Hematopathology, University of Pittsburgh School of Medicine, Pittsburgh, PA †National Cancer Institute, Bethesda, MD #Massachusetts General Hospital, Harvard Medical School, Boston, MA ††Clarient Diagnostic Services Inc., A GE Healthcare Company, Aliso Viejo, CA ‡IUC-T-Oncopole, Toulouse, France ¶Department of Pathology, Inserm U955, Hôpital Henri Mondor, Université Paris-Est, Créteil, France §Queen Elizabeth Hospital, Hong Kong, SAR China ∥Institute of Pathology, University Hospital of Lausanne (CHUV), Lausanne, Switzerland **St Orsola Policlinic, Bologna University School of Medicine, Bologna, Italy.
Elaine S Jaffe
Pierre Brousset
John K C Chan
Laurence de Leval
Philippe Gaulard
Nancy Lee Harris
Stefano Pileri
Lawrence M Weiss
International Lymphoma Study Group
National Cancer Institute · USUniversity of Pittsburgh · USHarvard University · USInserm · FRInstitut universitaire du cancer de Toulouse Oncopole · FRQueen Elizabeth Hospital · CNUniversity Hospital of Lausanne · CH

Funding

Lymphoma Disease Discovery and DefintionZIASC000550 · NCI · DIVISION OF CLINICAL SCIENCES - NCI · PI JAFFE, ELAINE · 2009 to 2025
$16.9M
Hematopathology DiagnosisZIABC011070 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI JAFFE, ELAINE · 2009 to 2025
$14.5M
Hematopathology diagnosis and educationZ01BC011070 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI JAFFE, ELAINE · 2008 to 2008
$737k
Intramural NIH HHS Z01 BC011070
6 · The paper itself

Abstract

The cytotoxic T-cell and natural killer (NK)-cell lymphomas and related disorders are important but relatively rare lymphoid neoplasms that frequently are a challenge for practicing pathologists. This selective review, based on a meeting of the International Lymphoma Study Group, briefly reviews T-cell and NK-cell development and addresses questions related to the importance of precise cell lineage (αβ-type T cell, γδ T cell, or NK cell), the implications of Epstein-Barr virus infection, the significance of anatomic location including nodal disease, and the question of further categorization of enteropathy-associated T-cell lymphomas. Finally, developments subsequent to the 2008 World Health Organization Classification, including the recognition of indolent NK-cell and T-cell disorders of the gastrointestinal tract are presented.

Indexed as

Killer Cells, NaturalT-Lymphocytes, CytotoxicBiomarkers, TumorBiopsyCell LineageDiagnosis, DifferentialEnteropathy-Associated T-Cell LymphomaHerpesvirus 4, HumanHumansImmunohistochemistryLymphoma, T-CellPredictive Value of TestsPrognosisReceptors, Antigen, T-CellBiomarkers, TumorReceptors, Antigen, T-Cell

Identifiers

PMID25025449
PMCPMC6329302
OpenAlexW2090561274

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.