Wnt/β-catenin and transforming growth factor-β signaling in pulmonary fibrosis. A case for antagonistic pleiotropy?

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

9 citing papers in PubMed.

1. AhR Mediated Activation of Pro-Inflammatory Response of RAW 264.7 Cells Modulate the Epithelial-Mesenchymal Transition.Toxics · 2022
   Article
2. Tartrate-resistant acid phosphatase 5 promotes pulmonary fibrosis by modulating β-catenin signaling.Nature communications · 2022
   Article
3. Wnt Signaling Is Deranged in Asthmatic Bronchial Epithelium and Fibroblasts.Frontiers in cell and developmental biology · 2021
   Article
4. Lysyl hydroxylase 3 increases collagen deposition and promotes pulmonary fibrosis by activating TGFβ1/Smad3 and Wnt/β-catenin pathways.Archives of medical science : AMS · 2020
   Article
5. Re-expression of pro-fibrotic, embryonic preserved mediators in irradiated arterial vessels of the head and neck region.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2017
   Article
6. Activation of Wnt/β-catenin signalling is required for TGF-β/Smad2/3 signalling during myofibroblast proliferation.Journal of cellular and molecular medicine · 2017
   Article
7. Aberrant Wnt/Beta-Catenin Pathway Activation in Dialysate-Induced Peritoneal Fibrosis.Frontiers in pharmacology · 2017
   Article
8. Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD.The Journal of experimental medicine · 2017
   Article
9. Transforming growth factor β regulates β-catenin expression in lung fibroblast through NF-κB dependent pathway.International journal of molecular medicine · 2014
   Article

Corrections and comments

• Comment on
  Wnt coreceptor Lrp5 is a driver of idiopathic pulmonary fibrosis.2014

Authors and funding

2 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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