Evidence map›Paper›PMID 25025344›Full record

ArticlePloS one2014

Seasonal incidence of medically attended respiratory syncytial virus infection in a community cohort of adults ≥50 years old.

David L McClure, Burney A Kieke, Maria E Sundaram, Melissa D Simpson, Jennifer K Meece, Frangiscos Sifakis, Robert A Gasser, Edward A Belongia

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 3 pooled it
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 3 syntheses or guidelines pooled it, 88 citations in OpenAlex.

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  20. Epidemiology of Respiratory Syncytial Virus in Adults and Children With Medically Attended Acute Respiratory Illness Over Three Seasons.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

David L McClureMarshfield Clinic Research Foundation, Marshfield, Wisconsin, United States of America.
Burney A KiekeMarshfield Clinic Research Foundation, Marshfield, Wisconsin, United States of America.
Maria E SundaramMarshfield Clinic Research Foundation, Marshfield, Wisconsin, United States of America.
Melissa D SimpsonMarshfield Clinic Research Foundation, Marshfield, Wisconsin, United States of America.
Jennifer K MeeceMarshfield Clinic Research Foundation, Marshfield, Wisconsin, United States of America.
Frangiscos SifakisMedImmune LLC, Gaithersburg, Maryland, United States of America.
Robert A GasserMedImmune LLC, Gaithersburg, Maryland, United States of America.
Edward A BelongiaMarshfield Clinic Research Foundation, Marshfield, Wisconsin, United States of America.
Marshfield Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiagnostic testing for respiratory syncytial virus (RSV) is not routinely performed in adults. We estimated medically attended RSV seasonal incidence in a community cohort of adults ≥50 years old during four influenza seasons (2006-07 through 2009-10).

methodsPatients seeking care for acute respiratory illness (ARI) were prospectively enrolled and tested for RSV by multiplex RT-PCR. Results from enrolled patients were used to estimate projected cases among non-enrolled patients with ARI. The seasonal incidence of medically attended RSV was the sum of actual and projected cases divided by the community cohort denominator. Since each enrollment period did not include the entire RSV season, incidence estimates were adjusted to account for the statewide proportion of RSV occurring outside the study enrollment period.

resultsThere were 16,088 to 17,694 adults in the cohort each season and 164 RSV cases in all 4 seasons. The overall seasonal incidence of medically attended RSV was 154 episodes (95% CI, 132-180) per 10,000 persons; the incidence was highest in 2007-08 (179) and lowest in 2006-07 (110). Among persons 50-59, 60-69, and ≥70 years old, RSV incidence was 124 (95% CI, 99-156), 147 (95% CI, 110-196), and 199 (95% CI, 153-258), respectively.

conclusionsThe incidence of medically attended RSV increased with age and was similar during four seasons.

Indexed as

AdultAgedCommunity-Acquired InfectionsFemaleHumansIncidenceMaleMiddle AgedResidence CharacteristicsRespiratory Syncytial Virus InfectionsSeasonsWisconsin

Identifiers

PMID25025344
PMCPMC4099308
OpenAlexW1998439719

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.