Evidence map›Paper›PMID 25025070›Full record

ReviewBioMed research international2014

Sexual enhancement products for sale online: raising awareness of the psychoactive effects of yohimbine, maca, horny goat weed, and Ginkgo biloba.

Ornella Corazza, Giovanni Martinotti, Rita Santacroce, Eleonora Chillemi, Massimo Di Giannantonio, Fabrizio Schifano, Selim Cellek

Abstract readReview
In one paragraph

Review in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Medicina (Kaunas, Lithuania) · 2022
    Pooled it
  2. Guideline
  3. Pooled it
  4. Trial
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ornella CorazzaSchool of Life and Medical Sciences, University of Hertfordshire, College Lane, Hatfield AL10 9AB, UK.
Giovanni MartinottiDepartment of Neuroscience and Imaging, University "G. d'Annunzio", 66100 Chieti, Italy.
Rita SantacroceSchool of Life and Medical Sciences, University of Hertfordshire, College Lane, Hatfield AL10 9AB, UK ; Department of Neuroscience and Imaging, University "G. d'Annunzio", 66100 Chieti, Italy.
Eleonora ChillemiDepartment of Neuroscience and Imaging, University "G. d'Annunzio", 66100 Chieti, Italy.
Massimo Di GiannantonioDepartment of Neuroscience and Imaging, University "G. d'Annunzio", 66100 Chieti, Italy.
Fabrizio SchifanoSchool of Life and Medical Sciences, University of Hertfordshire, College Lane, Hatfield AL10 9AB, UK.
Selim CellekCranfield University, Bedfordshire MK43 0AL, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe use of unlicensed food and herbal supplements to enhance sexual functions is drastically increasing. This phenomenon, combined with the availability of these products over the Internet, represents a challenge from a clinical and a public health perspective.

methodsA comprehensive multilingual assessment of websites, drug fora, and other online resources was carried out between February and July 2013 with exploratory qualitative searches including 203 websites. Additional searches were conducted using the Global Public Health Intelligence Network (GPHIN). Once the active constitutes of the products were identified, a comprehensive literature search was carried out using PsycInfo and PubMed.

resultsThe most common sexual enhancement products available on the Internet were identified. Their active ingredients included yohimbine, maca, horny goat weed and Ginkgo biloba. These four substances were reported with the occurrence of adverse events and the induction of psychological symptoms, such as mood changes, anxiety, and hallucinations as well as addictive behaviours.

conclusionsUncontrolled availability of sexual enhancement products that contain potentially harmful substances is a major public health concern. The possible impact on population health, particularly among subjects with psychiatric disorders, usually at risk for sexual dysfunction, may be significant. This new trend needs to be extensively studied and monitored.

Indexed as

Ginkgo bilobaHumansLepidiumPharmaceutical Services, OnlineSexual BehaviorSexual Dysfunctions, PsychologicalYohimbineYohimbine

Identifiers

PMID25025070
PMCPMC4082836

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.