ArticleBioMed research international2014
The association between platelet count and acute phase response in chronic spontaneous urticaria.
Article in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 43 citations in OpenAlex.
- The effect of omalizumab treatment on inflammatory parameters in urticarial diseases: a retrospective study.Postepy dermatologii i alergologii · 2026Article
- Article
- Role of Platelet-Activating Factor in the Pathogenesis of Chronic Spontaneous Urticaria.International journal of molecular sciences · 2024Review
- Pilot Study of Use of Nitric Oxide in Monitoring Multiple Dental Foci in Oral Cavity-A Case Report.Healthcare (Basel, Switzerland) · 2022Article
- Evaluation of carotid intima media thickness and hematologic inflammatory markers in patients with chronic spontaneous urticaria.Postepy dermatologii i alergologii · 2020Article
- Biomarkers In Chronic Spontaneous Urticaria: Current Targets And Clinical Implications.Journal of asthma and allergy · 2019Article
- [Clinical characteristics of urticaria in children versus adults].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2017Article
- Diagnostic values of red cell distribution width, platelet distribution width and neutrophil-lymphocyte count ratio for sepsis.Experimental and therapeutic medicine · 2016Article
- Analysis of circulating vascular endothelial growth factor and its soluble receptors in patients with different forms of chronic urticaria.BioMed research international · 2015Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe platelet parameters and C-reactive protein (CRP) are markers reflecting a systemic inflammatory response. Among those, CRP is one of the major proteins helpful in determination of severity/activity of chronic spontaneous urticaria (CSU).
aimTo determine relationships between platelet activation indices and serum concentration of CRP, the best marker of acute phase response, and their potential clinical use in CSU patients.
methodsMean platelet volume (MPV), platelet distribution width (PDW), and platelet count as well as serum CRP concentration were measured in CSU patients, showing different degrees of urticarial severity, and in the healthy subjects.
resultsNo significant differences were found in MPV and PDW between CSU group and the healthy subjects. The platelet count was significantly higher in moderate-severe CSU than that of the controls and mild CSU patients. Serum CRP concentrations were significantly higher in CSU patients as compared with the healthy subjects and significantly correlated with the platelet count in CSU patients.
conclusionsAcute phase response in CSU is associated with the increased number of circulating platelets in patients with more severe symptoms. It seems that simple determination of platelet size indices is not a reliable indicator of CSU severity/activity.
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