ArticleJournal of clinical oncology : official journal of the American Society of Clinical Oncology2014
Developmental and adaptive functioning in children with retinoblastoma: a longitudinal investigation.
Article in Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 32 citations in OpenAlex.
- Participation in an occupational therapy referral program for children with retinoblastoma.Journal of pediatric rehabilitation medicine · 2016Trial
- Retinoblastoma and vision.Eye (London, England) · 2023Review
- An exploratory study of sleep habits in school-aged survivors of retinoblastoma.Sleep medicine · 2023Article
- Prenatal ambient pesticide exposure and childhood retinoblastoma.International journal of hygiene and environmental health · 2022Article
- Cognitive and Adaptive Functioning in Youth With Retinoblastoma: A Longitudinal Investigation Through 10 Years of Age.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2021Article
- Retinoblastoma management in 13q deletion syndrome patients using super-selective chemotherapies and other cancer-directed interventions.Pediatric blood & cancer · 2021Article
- The Influence of Early Childhood Temperament on Later Social-Emotional Functioning in Youth with Cancer.Journal of pediatric psychology · 2021Article
- Impact of enucleation on adult retinoblastoma survivors' quality of life: A qualitative study of survivors' perspectives.Palliative & supportive care · 2020Article
- Early Cognitive and Adaptive Functioning of Clinically Referred Infants and Toddlers with Cancer.Journal of clinical psychology in medical settings · 2020Article
- Trajectories of psychosocial and cognitive functioning in pediatric patients with brain tumors treated with radiation therapy.Neuro-oncology · 2019Article
- Growth patterns of survivors of retinoblastoma treated with ophthalmic artery chemosurgery.PloS one · 2018Article
- Questionnaire study to gain an insight into the manufacturing and fitting process of artificial eyes in children: an ocularist perspective.International ophthalmology · 2017Article
- A longitudinal investigation of parenting stress in caregivers of children with retinoblastoma.Pediatric blood & cancer · 2017Article
- Retinoblastoma.Nature reviews. Disease primers · 2015Review
- Management of retinoblastoma in children: current status.Paediatric drugs · 2015Review
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
purposeTo determine the developmental trajectory of early cognitive and adaptive skills in young children with retinoblastoma from diagnosis to 5 years of age. PATIENTS AND
methodsNinety-four patients with retinoblastoma treated according to an institutional protocol underwent serial assessments of cognitive and adaptive functioning at age 6 months and 1, 2, 3, and 5 years. Data were analyzed by treatment strata, with patients with 13q deletion analyzed separately.
resultsAt baseline, across all patients (except those with 13q deletion), developmental functioning was comparable with the normative mean, with mean scores for all strata within the average range. However, at age 5 years, developmental functioning was in the low average range and significantly below normative means. The trajectories of developmental functioning demonstrated significant decline over time, although this varied by treatment group/strata. Patients treated with enucleation only evidenced the greatest decline in cognitive functioning; significant change was not observed in patients treated with other modalities. Notable declines in parent-reported communication skills were observed in the majority of patients. Patients with 13q deletion evidenced delayed cognitive functioning at baseline, but minimal declines were observed through age 3 years. However, significant decreases in adaptive functioning were demonstrated over time for the 13q deletion subset.
conclusionThe declines in functioning observed in this study were unexpected, as was the poorer performance of the enucleation-only group. This highlights the necessity of continuing to assess cognitive functioning in patients with retinoblastoma as they age. Additional research is necessary to determine the long-term trajectory of cognitive development in this population.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.