ReviewCurrent psychiatry reports2014
Current understanding of the neurobiology and longitudinal course of geriatric depression.
Review in Current psychiatry reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- The Role of State Versus Trait Anxiety on Cognition in Older Adults With Major Depressive Disorder.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2024Observational
- Be Fit, Be Sharp, Be Well: The Case for Exercise as a Treatment for Cognitive Impairment in Late-life Depression.Journal of the International Neuropsychological Society : JINS · 2021Review
- Crosstalk between Depression and Dementia with Resting-State fMRI Studies and Its Relationship with Cognitive Functioning.Biomedicines · 2021Review
- Article
- Stopping Cognitive Decline in Patients With Late-Life Depression: A New Front in the Fight Against Dementia.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2018Article
- Genome-wide scan of depressive symptomatology in two representative cohorts in the United States and the United Kingdom.Journal of psychiatric research · 2018Article
- Editorial Comment: Stress and Late-Life Depression.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2017Article
- Physical Activity Modulates Common Neuroplasticity Substrates in Major Depressive and Bipolar Disorder.Neural plasticity · 2017Review
- Zinc transporters protein level in postmortem brain of depressed subjects and suicide victims.Journal of psychiatric research · 2016Article
- [Depression in old age, part 1 : Origin, clinical symptoms, diagnosis and interaction between depression and dementia].Zeitschrift fur Gerontologie und Geriatrie · 2016Article
- Association of Cerebral Amyloidosis, Blood Pressure, and Neuronal Injury with Late-Life Onset Depression.Frontiers in aging neuroscience · 2016Article
- Is cognitive lifestyle associated with depressive thoughts and self-reported depressive symptoms in later life?European journal of ageingArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Late life depression is a complex disease associated with a number of contributing neurobiological factors, including cerebrovascular disease, neurodegeneration, and inflammation, which also contribute to its longitudinal prognosis and course. These factors create a context in which the brain is more vulnerable to the impact of stress, and thus, to depression. At the same time, some individuals are protected from late life depression and its consequences, even in the face of neurobiological vulnerability, through benefitting from one or more attributes associated with resilience, including social support, engagement in physical and cognitive activities, and brain reserve. Enhanced understanding of how neurobiological and environmental factors interact in predicting vulnerability and resilience is needed to predict onset and course of depression in late life and develop more effective interventions.
Indexed as
Identifiers
25023511What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.