ReviewAdvances in nutrition (Bethesda, Md.)2014
Relations between metabolic homeostasis, diet, and peripheral afferent neuron biology.
Review in Advances in nutrition (Bethesda, Md.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 19 citations in OpenAlex.
- Precision Nutrition Unveiled: Gene-Nutrient Interactions, Microbiota Dynamics, and Lifestyle Factors in Obesity Management.Nutrients · 2024Review
- Spinal afferent neurons: emerging regulators of energy balance and metabolism.Frontiers in molecular neuroscience · 2024Review
- Patchouli alcohol improved diarrhea-predominant irritable bowel syndrome by regulating excitatory neurotransmission in the myenteric plexus of rats.Frontiers in pharmacology · 2022Article
- Coupling of energy intake and energy expenditure across a temperature spectrum: impact of diet-induced obesity in mice.American journal of physiology. Endocrinology and metabolism · 2020Article
- Increased intestinal mucosal leptin levels in patients with diarrhea-predominant irritable bowel syndrome.World journal of gastroenterology · 2018Article
- Gastrointestinal hormones and the gut connectome.Current opinion in endocrinology, diabetes, and obesity · 2017Review
- Lipolysis sensation by white fat afferent nerves triggers brown fat thermogenesis.Molecular metabolism · 2016Article
- Article
- Peripheral neuropathy is associated with insulin resistance independent of metabolic syndrome.Diabetology & metabolic syndrome · 2015Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It is well established that food intake behavior and energy balance are regulated by crosstalk between peripheral organ systems and the central nervous system (CNS), for instance, through the actions of peripherally derived leptin on hindbrain and hypothalamic loci. Diet- or obesity-associated disturbances in metabolic and hormonal signals to the CNS can perturb metabolic homeostasis bodywide. Although interrelations between metabolic status and diet with CNS biology are well characterized, afferent networks (those sending information to the CNS from the periphery) have received far less attention. It is increasingly appreciated that afferent neurons in adipose tissue, the intestines, liver, and other tissues are important controllers of energy balance and feeding behavior. Disruption in their signaling may have consequences for cardiovascular, pancreatic, adipose, and immune function. This review discusses the diverse ways that afferent neurons participate in metabolic homeostasis and highlights how changes in their function associate with dysmetabolic states, such as obesity and insulin resistance.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.