Evidence map›Paper›PMID 25022610›Full record

ReviewTravel medicine and infectious disease

Risk factors associated with malaria deaths in travellers: a literature review.

Beda Lüthi, Patricia Schlagenhauf

Abstract readReview
PubMed Publisher
In one paragraph

Review in Travel medicine and infectious disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
6.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 70 citations in OpenAlex.

  1. Healthcare-associated malaria: a systematic review, 1997 to 2023.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025
    Pooled it
  2. Article
  3. A Severe Case ofLife (Basel, Switzerland) · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Mortality from malaria in France, 2005 to 2014.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2020
    Article
  13. Observational
  14. Article
  15. Observational
  16. Article
  17. Obesity and Diabetes as Risk Factors for Severe Plasmodium falciparum Malaria: Results From a Swedish Nationwide Study.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2017
    Observational
  18. Article
  19. Article
  20. Observational
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Beda LüthiUniversity of Zürich Centre for Travel Medicine, WHO Collaborating Centre for Travellers' Health, Hirschengraben 84, CH-8001 Zürich, Switzerland. Electronic address: beda.luethi@uzh.ch.
Patricia SchlagenhaufUniversity of Zürich Centre for Travel Medicine, WHO Collaborating Centre for Travellers' Health, Hirschengraben 84, CH-8001 Zürich, Switzerland. Electronic address: pat@ifspm.uzh.ch.
University of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malaria is the most frequently imported acute, life-treating, tropical disease in international travellers. We did a literature review in PubMed using pre-defined search terms to identify possible risk factors for malaria deaths in travellers. After screening, a total of 51 papers were selected for inclusion and were intensively scrutinised for details of "case fatality rates" and risk factors for fatal malaria associated with travel. The main risk factors were: non-use or inappropriate use of chemoprophylaxis, age, delay in seeking care, incorrect treatment, delay in diagnosis, infection with Plasmodium falciparum, non-immunity, travelling as a tourist and sex. The "case fatality rate" in most of the studies lay in the range 0.2%-3%. Possible reasons for this case fatality rate variation are: small case series, different populations included in the studies with different physiological and social determinants, including different species of malaria parasite and different traveller destinations in the case series.

Indexed as

TravelAge FactorsAntimalarialsDelayed DiagnosisFemaleHumansMalariaMalaria, FalciparumMaleMortalityPre-Exposure ProphylaxisRisk FactorsSex FactorsAntimalarialsCo-morbiditiesFatalMalariaRisk factorsTraveller

Identifiers

PMID25022610
OpenAlexW1964862026

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.