Evidence map›Paper›PMID 25022589›Full record

ArticleAntimicrobial agents and chemotherapy2014

Comparison of different drug susceptibility test methods to detect rifampin heteroresistance in Mycobacterium tuberculosis.

Zhijian Zhang, Yufeng Wang, Yu Pang, Changting Liu

Abstract readComparative Study
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Ultrasensitive Detection of Multidrug-ResistantInternational journal of molecular sciences · 2022
    Article
  3. Article
  4. Rarity ofInfection and drug resistance · 2021
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Cryptic Microheteroresistance Explains Mycobacterium tuberculosis Phenotypic Resistance.American journal of respiratory and critical care medicine · 2017
    Article
  10. Article
  11. Article
  12. Prothionamide susceptibility testing of Mycobacterium tuberculosis using the resazurin microtitre assay and the BACTECMGIT 960 system.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2017
    Article
  13. Article
  14. Article
  15. Article
  16. Factors Associated with Missed Detection ofBioMed research international · 2016
    Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zhijian ZhangRespiratory Diseases Department of Nanlou, Chinese People's Liberation Army General Hospital, Beijing, China National Center for Tuberculosis Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Yufeng WangNational Center for Tuberculosis Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Yu PangRespiratory Diseases Department of Nanlou, Chinese People's Liberation Army General Hospital, Beijing, China National Center for Tuberculosis Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China pangyu@chinatb.org liuchangting301@163.com.
Changting LiuRespiratory Diseases Department of Nanlou, Chinese People's Liberation Army General Hospital, Beijing, China pangyu@chinatb.org liuchangting301@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We compared the efficiencies of different drug susceptibility testing methods in detecting rifampin (RIF) heteroresistance in Mycobacterium tuberculosis. Our data revealed that the broth dilution method found more resistance than MGIT did (P=0.046) for the low-resistance group. Similarly, the broth dilution method was more sensitive in detecting RIF heteroresistance in subpopulations with low growth rates than was MGIT (P=0.033). In conclusion, our data demonstrated that the broth dilution method was more sensitive than MGIT in detecting RIF heteroresistance.

Indexed as

Antibiotics, AntitubercularBacterial ProteinsDNA-Directed RNA PolymerasesMicrobial Sensitivity TestsMycobacterium tuberculosisRifampinAntibiotics, AntitubercularBacterial ProteinsDNA-Directed RNA PolymerasesRifampinrpoB protein, Mycobacterium tuberculosis

Identifiers

PMID25022589
PMCPMC4135805

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.