Evidence map›Paper›PMID 25022452›Full record

ArticlePhysica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)2014

Non-rigid registration of serial dedicated breast CT, longitudinal dedicated breast CT and PET/CT images using the diffeomorphic demons method.

Jonathan Santos, Abhijit J Chaudhari, Anand A Joshi, Andrea Ferrero, Kai Yang, John M Boone, Ramsey D Badawi

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 15 citations in OpenAlex.

  1. Fully Automated, Fast Motion Correction of Dynamic Whole-Body and Total-Body PET/CT Imaging Studies.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
    Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jonathan SantosDepartment of Radiology, University of California-Davis School of Medicine, Sacramento, CA 95817, USA.
Abhijit J ChaudhariDepartment of Radiology, University of California-Davis School of Medicine, Sacramento, CA 95817, USA. Electronic address: ajchaudhari@ucdavis.edu.
Anand A JoshiSignal and Image Processing Institute, University of Southern California, Los Angeles, CA 90089, USA.
Andrea FerreroDepartment of Biomedical Engineering, University of California-Davis, Davis, CA 95616, USA.
Kai YangDepartment of Radiology, University of California-Davis School of Medicine, Sacramento, CA 95817, USA.
John M BooneDepartment of Radiology, University of California-Davis School of Medicine, Sacramento, CA 95817, USA; Department of Biomedical Engineering, University of California-Davis, Davis, CA 95616, USA.
Ramsey D BadawiDepartment of Radiology, University of California-Davis School of Medicine, Sacramento, CA 95817, USA; Department of Biomedical Engineering, University of California-Davis, Davis, CA 95616, USA.
University of California, Davis · USUniversity of Southern California · US

Funding

Building Interdisciplinary Research Careers in Womens Health at UC Davis - Administrative SupplementK12HD051958 · NICHD · UNIVERSITY OF CALIFORNIA DAVIS · PI LANE, NANCY E · 2005 to 2023
$9.6M
Breast CT scanner for earlier cancer detectionR01EB002138 · NIBIB · UNIVERSITY OF CALIFORNIA DAVIS · PI BOONE, JOHN M · 2003 to 2012
$9.0M
Dedicated High-Performance Breast PET/CTR01CA129561 · NCI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BADAWI, RAMSEY D. · 2009 to 2013
$3.5M
Quasi-rigid image registration for DCE-MRIR03EB015099 · NIBIB · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CHAUDHARI, ABHIJIT J · 2013 to 2014
$143k
NCI NIH HHS R01 CA129561NCI NIH HHS R01 CA129561S1NIBIB NIH HHS R01 EB002138NIBIB NIH HHS R01EB002138NIBIB NIH HHS R03 EB015099NICHD NIH HHS K12 HD051958
6 · The paper itself

Abstract

RATIONALE AND

objectivesDedicated breast CT and PET/CT scanners provide detailed 3D anatomical and functional imaging data sets and are currently being investigated for applications in breast cancer management such as diagnosis, monitoring response to therapy and radiation therapy planning. Our objective was to evaluate the performance of the diffeomorphic demons (DD) non-rigid image registration method to spatially align 3D serial (pre- and post-contrast) dedicated breast computed tomography (CT), and longitudinally-acquired dedicated 3D breast CT and positron emission tomography (PET)/CT images.

methodsThe algorithmic parameters of the DD method were optimized for the alignment of dedicated breast CT images using training data and fixed. The performance of the method for image alignment was quantitatively evaluated using three separate data sets; (1) serial breast CT pre- and post-contrast images of 20 women, (2) breast CT images of 20 women acquired before and after repositioning the subject on the scanner, and (3) dedicated breast PET/CT images of 7 women undergoing neo-adjuvant chemotherapy acquired pre-treatment and after 1 cycle of therapy.

resultsThe DD registration method outperformed no registration (p < 0.001) and conventional affine registration (p ≤ 0.002) for serial and longitudinal breast CT and PET/CT image alignment. In spite of the large size of the imaging data, the computational cost of the DD method was found to be reasonable (3-5 min).

conclusionsCo-registration of dedicated breast CT and PET/CT images can be performed rapidly and reliably using the DD method. This is the first study evaluating the DD registration method for the alignment of dedicated breast CT and PET/CT images.

Indexed as

AlgorithmsBreastBreast NeoplasmsFemaleHumansImage Processing, Computer-AssistedMammographyPositron-Emission TomographyTime FactorsTomography, X-Ray ComputedBreast PET/CTDedicated breast CTDiffeomorphic demonsNon-rigid registration

Identifiers

PMID25022452
PMCPMC4138248
OpenAlexW1968103318

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.