Evidence map›Paper›PMID 25022264›Full record

ArticleMycopathologia2014

Occurrence and characterization of Candida nivariensis from a culture collection of Candida glabrata clinical isolates in Malaysia.

Sun Tee Tay, Azadeh Lotfalikhani, Negar Shafiei Sabet, Sasheela Ponnampalavanar, Sofiah Sulaiman, Shiang Ling Na, Kee Peng Ng

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Mycopathologia, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Global Epidemiology of Invasive Infections by UncommonJournal of fungi (Basel, Switzerland) · 2024
    Review
  2. Three cases of vulvovaginal candidiasis due toMedical mycology case reports · 2024
    Article
  3. Overview on the Infections Related to RarePathogens (Basel, Switzerland) · 2022
    Review
  4. Pharmaceutics · 2021
    Review
  5. Journal of fungi (Basel, Switzerland) · 2021
    Review
  6. First Isolation of Candida nivariensis, an Emerging Fungal Pathogen, in Kuwait.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2021
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sun Tee TayDepartment of Medical Microbiology, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia, tayst@um.edu.my.
Azadeh Lotfalikhani
Negar Shafiei Sabet
Sasheela Ponnampalavanar
Sofiah Sulaiman
Shiang Ling Na
Kee Peng Ng

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCandida nivariensis and C. bracarensis have been recently identified as emerging yeast pathogens which are phenotypically indistinguishable from C. glabrata. However, there is little data on the prevalence and antifungal susceptibilities of these species.

objectiveThis study investigated the occurrence of C. nivariensis and C. bracarensis in a culture collection of 185 C. glabrata isolates at a Malaysian teaching hospital.

methodsC. nivariensis was discriminated from C. glabrata using a PCR assay as described by Enache-Angoulvant et al. (J Clin Microbiol 49:3375-9, 2011). The identity of the isolates was confirmed by sequence analysis of the D1D2 domain and internal transcribed spacer region of the yeasts. The isolates were cultured on Chromogenic CHROMagar Candida (®) agar (Difco, USA), and their biochemical and enzymic profiles were determined. Antifungal susceptibilities of the isolates against amphotericin B, fluconazole, voriconazole and caspofungin were determined using E tests. Clotrimazole MICs were determined using a microbroth dilution method.

resultsThere was a low prevalence (1.1 %) of C. nivariensis in our culture collection of C. glabrata. C. nivariensis was isolated from a blood culture and vaginal swab of two patients. C. nivariensis grew as white colonies on Chromogenic agar and demonstrated few positive reactions using biochemical tests. Enzymatic profiles of the C. nivariensis isolates were similar to that of C. glabrata. The isolates were susceptible to amphotericin B, fluconazole, voriconazole and caspofungin. Clotrimazole resistance is suspected in one isolate.

conclusionThis study reports for the first time the emergence of C. nivariensis in our clinical setting.

Indexed as

AdultAgedAntifungal AgentsCandidaCandidiasisCluster AnalysisCulture MediaDNA, FungalDNA, Ribosomal SpacerHospitals, TeachingHumansMalaysiaMicrobial Sensitivity TestsMicrobiological TechniquesMolecular Sequence DataMycological Typing TechniquesAntifungal AgentsCulture MediaDNA, FungalDNA, Ribosomal Spacer

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.