ArticlePloS one2014
Visualization and analysis of hepatitis C virus structural proteins at lipid droplets by super-resolution microscopy.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 25 citations in OpenAlex.
- Measles virus reprograms CD4Frontiers in cell and developmental biology · 2026Article
- Dynamics and Patterning of 5-Hydroxytryptamine 2 Subtype Receptors in JC Polyomavirus Entry.Viruses · 2022Article
- Indane-1,3-Dione: From Synthetic Strategies to Applications.Molecules (Basel, Switzerland) · 2022Review
- Direct Stochastic Optical Reconstruction Microscopy of Extracellular Vesicles in Three Dimensions.Journal of visualized experiments : JoVE · 2021Article
- Optical technologies for the detection of viruses like COVID-19: Progress and prospects.Biosensors & bioelectronics · 2021Review
- Hepatitis C virus infection restricts human LINE-1 retrotransposition in hepatoma cells.PLoS pathogens · 2021Article
- Towards a Quantitative Single Particle Characterization by Super Resolution Microscopy: From Virus Structures to Antivirals Design.Frontiers in bioengineering and biotechnology · 2021Review
- Visualisation and analysis of hepatitis C virus non-structural proteins using super-resolution microscopy.Scientific reports · 2018Article
- Photoactivatable aggregation-induced emission probes for lipid droplets-specific live cell imaging.Chemical science · 2017Article
- Microscopy tools for the investigation of intracellular lipid storage and dynamics.Molecular metabolism · 2016Review
- Superresolution imaging of viral protein trafficking.Medical microbiology and immunology · 2015Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cytosolic lipid droplets are central organelles in the Hepatitis C Virus (HCV) life cycle. The viral capsid protein core localizes to lipid droplets and initiates the production of viral particles at lipid droplet-associated ER membranes. Core is thought to encapsidate newly synthesized viral RNA and, through interaction with the two envelope proteins E1 and E2, bud into the ER lumen. Here, we visualized the spatial distribution of HCV structural proteins core and E2 in vicinity of small lipid droplets by three-color 3D super-resolution microscopy. We observed and analyzed small areas of colocalization between the two structural proteins in HCV-infected cells with a diameter of approximately 100 nm that might represent putative viral assembly sites.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.