Evidence map›Paper›PMID 25019068›Full record

ArticleFrontiers in cell and developmental biology2014

Gβ1γ2 activates phospholipase A

Marie E Bechler, William J Brown

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. CaFaculty reviews · 2022
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Marie E BechlerDepartment of Molecular Biology and Genetics, Cornell University, Ithaca, NY, USA.
William J BrownDepartment of Molecular Biology and Genetics, Cornell University, Ithaca, NY, USA.
Cornell University · US

Funding

MEMBRANE TRAFFICKING IN MAMMALIAN CELLSR01DK051596 · NIDDK · CORNELL UNIVERSITY ITHACA · PI BROWN, WILLIAM J · 1996 to 2009
$3.0M
Role of Phospholipid Remodeling in Secretion and Golgi Function in Mammalian CellR01GM101027 · NIGMS · CORNELL UNIVERSITY · PI BROWN, WILLIAM J · 2013 to 2016
$1.2M
Membrane Trafficking in Mammalian CellsR56DK051596 · NIDDK · CORNELL UNIVERSITY · PI BROWN, WILLIAM J · 2010 to 2010
$239k
NIDDK NIH HHS R01 DK051596NIDDK NIH HHS R56 DK051596NIGMS NIH HHS R01 GM101027
6 · The paper itself

Abstract

Heterotrimeric G proteins transduce the ligand binding of transmembrane G protein coupled receptors into a variety of intracellular signaling pathways. Recently, heterotrimeric Gβγ subunit signaling at the Golgi complex has been shown to regulate the formation of vesicular transport carriers that deliver cargo from the Golgi to the plasma membrane. In addition to vesicles, membrane tubules have also been shown to mediate export from the Golgi complex, which requires the activity of cytoplasmic phospholipase A

Indexed as

Golgi complexGβγheterotrimeric G proteinsmembrane tubulesphospholipidsPLA2

Identifiers

PMID25019068
PMCPMC4091998
OpenAlexW2021553911

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.