Evidence map›Paper›PMID 25018852›Full record

ReviewWorld journal of hepatology2014

Management of hepatitis C virus infection in hemodialysis patients.

Yue-Cheng Yu, Yue Wang, Chang-Lun He, Mao-Rong Wang, Yu-Ming Wang

Open access · bronzeAbstract readReview
In one paragraph

Review in World journal of hepatology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
  4. Asunaprevir and daclatasvir in hemodialysis patients with chronic hepatitis C virus genotype 1b infection.JGH open : an open access journal of gastroenterology and hepatology · 2017
    Article
  5. Article
  6. Observational
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yue-Cheng YuYue-Cheng Yu, Chang-Lun He, Mao-Rong Wang, Liver Diseases Center of PLA, the 81 Hospital of PLA, Nanjing University of Chinese Traditional Medicine, Nanjing 210002, Jiangsu Province, China.
Yue WangYue-Cheng Yu, Chang-Lun He, Mao-Rong Wang, Liver Diseases Center of PLA, the 81 Hospital of PLA, Nanjing University of Chinese Traditional Medicine, Nanjing 210002, Jiangsu Province, China.
Chang-Lun HeYue-Cheng Yu, Chang-Lun He, Mao-Rong Wang, Liver Diseases Center of PLA, the 81 Hospital of PLA, Nanjing University of Chinese Traditional Medicine, Nanjing 210002, Jiangsu Province, China.
Mao-Rong WangYue-Cheng Yu, Chang-Lun He, Mao-Rong Wang, Liver Diseases Center of PLA, the 81 Hospital of PLA, Nanjing University of Chinese Traditional Medicine, Nanjing 210002, Jiangsu Province, China.
Yu-Ming WangYue-Cheng Yu, Chang-Lun He, Mao-Rong Wang, Liver Diseases Center of PLA, the 81 Hospital of PLA, Nanjing University of Chinese Traditional Medicine, Nanjing 210002, Jiangsu Province, China.
81th Hospital of PLA · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The prevalence of hepatitis C virus (HCV) infection in patients on maintenance hemodialysis (MHD) is relatively higher than those without MHD. Chronic HCV infection detrimentally affects the life quality and expectancy, leads to renal transplant rejection, and increases the mortality of MHD patients. With the application of erythropoietin to improve uremic anemia and avoid blood transfusion, the new HCV infections during MHD in recent years are mainly caused by the lack of stringent universal precautions. Strict implementation of universal precautions for HCV transmission has led to markedly decreased HCV infections in many hemodialysis units, but physicians still should be alert for the anti-HCV negative HCV infection and occult HCV infection in MHD patients. Standard interferon alpha and pegylated interferon alpha monotherapies at a reduced dose are currently the main treatment strategies for MHD patients with active HCV replication, but how to increase the sustained virological response and decrease the side effects is the key problem. IFNα-free treatments with two or three direct-acting antivirals without ribavirin in MHD patients are waiting for future investigations.

Indexed as

EpidemiologyHemodialysisHepatitis C virusProphylaxisRisk factorsTreatment

Identifiers

PMID25018852
PMCPMC4081616
OpenAlexW1994943352

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.