ArticleInternational journal of clinical rheumatology2014
Future directions for the management of pain in osteoarthritis.
Article in International journal of clinical rheumatology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed, 47 citations in OpenAlex.
- The effectiveness of Kinesio TapingClinical rehabilitation · 2020Trial
- Next-Generation Hydrogel Design: Computational Advances in Synthesis, Characterization, and Biomedical Applications.Polymers · 2025Review
- Article
- Fatty Acids and Oxylipins in Osteoarthritis and Rheumatoid Arthritis-a Complex Field with Significant Potential for Future Treatments.Current rheumatology reports · 2021Review
- Efficacy of Methotrexate on Pain Severity Reduction and Improvement of Quality of Life in Patients with Moderate to Severe Knee Osteoarthritis.Anesthesiology and pain medicine · 2019Article
- Joint problems arising from lack of repair mechanisms: can cannabinoids help?British journal of pharmacology · 2019Review
- The effectiveness of Kinesio Taping® for pain management in knee osteoarthritis: a randomized, double-blind, controlled clinical trial.Therapeutic advances in musculoskeletal disease · 2019Article
- TGFβ1 induces hypertrophic change and expression of angiogenic factors in human chondrocytes.Oncotarget · 2017Article
- Patterns of intra-articular injection use after initiation of treatment in patients with knee osteoarthritis: data from the osteoarthritis initiative.Osteoarthritis and cartilage · 2017Article
- Efficacy of CR4056, a first-in-class imidazoline-2 analgesic drug, in comparison with naproxen in two rat models of osteoarthritis.Journal of pain research · 2017Article
- Possible role of the Ec peptide of IGF‑1Ec in cartilage repair.Molecular medicine reports · 2016Article
- Successful management of an equine carpal chip fracture by intra-articularly injected adipose-derived stromal vascular fraction after arthroscopic removal.Iranian journal of veterinary research · 2016Article
- Predictive factors and clinical biomarkers for treatment in patients with chronic pain caused by osteoarthritis with a central sensitisation component.International journal of clinical practice · 2016Review
- Indication of nerve growth factor binding components from herbal extracts by HerboChip: a platform for drug screening on a chip.Chinese medicine · 2016Article
- Safety issues of current analgesics: an update.Clujul medical (1957) · 2015Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Osteoarthritis (OA) is the predominant form of arthritis worldwide, resulting in a high degree of functional impairment and reduced quality of life owing to chronic pain. To date, there are no treatments that are known to modify disease progression of OA in the long term. Current treatments are largely based on the modulation of pain, including NSAIDs, opiates and, more recently, centrally acting pharmacotherapies to avert pain. This review will focus on the rationale for new avenues in pain modulation, including inhibition with anti-NGF antibodies and centrally acting analgesics. The authors also consider the potential for structure modification in cartilage/bone using growth factors and stem cell therapies. The possible mismatch between structural change and pain perception will also be discussed, introducing recent techniques that may assist in improved patient phenotyping of pain subsets in OA. Such developments could help further stratify subgroups and treatments for people with OA in future.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.