ArticleFrontiers in plant science2014
Duplications and losses in gene families of rust pathogens highlight putative effectors.
Article in Frontiers in plant science, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
27 citing papers in PubMed, 62 citations in OpenAlex.
- Article
- A Cystine Transporter Mediates Nutrient Acquisition and Redox Balance During Wheat Stripe Rust Infection.Molecular plant pathology · 2025Article
- Genomics Research on the Road of Studying Biology and Virulence of Cereal Rust Fungi.Molecular plant pathology · 2025Review
- The massive 340 megabase genome of Anisogramma anomala, a biotrophic ascomycete that causes eastern filbert blight of hazelnut.BMC genomics · 2024Article
- Systematic identification and functional characterization of the CFEM proteins in fishscale bamboo rhombic-spot pathogenFrontiers in plant science · 2024Article
- Major proliferation of transposable elements shaped the genome of the soybean rust pathogen Phakopsora pachyrhizi.Nature communications · 2023Article
- Exogenous double-stranded RNA inhibits the infection physiology of rust fungi to reduce symptoms in planta.Molecular plant pathology · 2023Article
- Comprehensive Analysis and Functional Verification of theInternational journal of molecular sciences · 2023Article
- Lifestyle Transitions in Fusarioid Fungi are Frequent and Lack Clear Genomic Signatures.Molecular biology and evolution · 2022Article
- Convergence Analysis of Rust Fungi and Anther Smuts Reveals Their Common Molecular Adaptation to a Phytoparasitic Lifestyle.Frontiers in genetics · 2022Article
- Characterization of two conserved cell death elicitor families from the Dothideomycete fungal pathogensFrontiers in microbiology · 2022Article
- A decade after the first Pucciniales genomes: A bibliometric snapshot of (post) genomics studies in three model rust fungi.Frontiers in microbiology · 2022Review
- Austropuccinia psidii, causing myrtle rust, has a gigabase-sized genome shaped by transposable elements.G3 (Bethesda, Md.) · 2021Article
- Comparative Transcriptomics and RNA-Seq-Based Bulked Segregant Analysis Reveals Genomic Basis UnderlyingFrontiers in microbiology · 2021Article
- Phylogenomic Analyses of Non-Dikarya Fungi Supports Horizontal Gene Transfer Driving Diversification of Secondary Metabolism in the Amphibian Gastrointestinal Symbiont,G3 (Bethesda, Md.) · 2020Article
- Network analysis exposes core functions in major lifestyles of fungal and oomycete plant pathogens.BMC genomics · 2019Article
- Comparative transcriptomics of Gymnosporangium spp. teliospores reveals a conserved genetic program at this specific stage of the rust fungal life cycle.BMC genomics · 2019Article
- Rapid turnover of effectors in grass powdery mildew (Blumeria graminis).BMC evolutionary biology · 2017Article
- Fungal Genomes and Insights into the Evolution of the Kingdom.Microbiology spectrum · 2017Article
- A fungal wheat pathogen evolved host specialization by extensive chromosomal rearrangements.The ISME journal · 2017Article
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rust fungi are a group of fungal pathogens that cause some of the world's most destructive diseases of trees and crops. A shared characteristic among rust fungi is obligate biotrophy, the inability to complete a lifecycle without a host. This dependence on a host species likely affects patterns of gene expansion, contraction, and innovation within rust pathogen genomes. The establishment of disease by biotrophic pathogens is reliant upon effector proteins that are encoded in the fungal genome and secreted from the pathogen into the host's cell apoplast or within the cells. This study uses a comparative genomic approach to elucidate putative effectors and determine their evolutionary histories. We used OrthoMCL to identify nearly 20,000 gene families in proteomes of 16 diverse fungal species, which include 15 basidiomycetes and one ascomycete. We inferred patterns of duplication and loss for each gene family and identified families with distinctive patterns of expansion/contraction associated with the evolution of rust fungal genomes. To recognize potential contributors for the unique features of rust pathogens, we identified families harboring secreted proteins that: (i) arose or expanded in rust pathogens relative to other fungi, or (ii) contracted or were lost in rust fungal genomes. While the origin of rust fungi appears to be associated with considerable gene loss, there are many gene duplications associated with each sampled rust fungal genome. We also highlight two putative effector gene families that have expanded in Cqf that we hypothesize have roles in pathogenicity.
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